Targeting Rev-Erbα to protect against ischemia-reperfusion-induced acute lung injury in rats

Targeting Rev-Erbα to protect against ischemia-reperfusion-induced acute lung injury in rats

Abstract Background The dysregulation of local circadian clock has been implicated in the pathogenesis of a broad spectrum of diseases. However, the pathophysiological role of intrinsic circadian clocks Rev-Erbα in ischemia-reperfusion (IR)-induced acute lung injury (ALI) remains unclear. Methods Th...

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Bibliographic Details
Main Authors:	Shi-Jye Chu, Wen-I Liao, Hsin-Ping Pao, Shu-Yu Wu, Shih-En Tang
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Series:	Respiratory Research
Subjects:	Acute lung injury Ischemia-reperfusion Circadian clocks Rev-Erbα SR9009 SR8278
Online Access:	https://doi.org/10.1186/s12931-023-02547-7

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