Integrative structure determination reveals functional global flexibility for an ultra-multimodular arabinanase
Lansky et al. describe the structural analysis of an ultra-multimodular GH43 arabinanase, AbnA. They discover a new carbohydrate binding module and analyze the large conformational transitions of the enzyme with the integrative structure determination approach, which may be applied to the conformati...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-03054-z |
| Summary: | Lansky et al. describe the structural analysis of an ultra-multimodular GH43 arabinanase, AbnA. They discover a new carbohydrate binding module and analyze the large conformational transitions of the enzyme with the integrative structure determination approach, which may be applied to the conformational studies of other ultramultimodular proteins as well. |
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| ISSN: | 2399-3642 |