Clinical outcomes stratified by baseline functional class after initial combination therapy for pulmonary arterial hypertension

Clinical outcomes stratified by baseline functional class after initial combination therapy for pulmonary arterial hypertension

Abstract Background Initial combination therapy with ambrisentan and tadalafil reduced the risk of clinical failure events for treatment-naïve participants with pulmonary arterial hypertension (PAH) as compared to monotherapy. Previous studies in PAH have demonstrated greater treatment benefits in m...

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Bibliographic Details
Main Authors: R. James White, Anton Vonk-Noordegraaf, Stephan Rosenkranz, Ronald J. Oudiz, Vallerie V. McLaughlin, Marius M. Hoeper, Ekkehard Grünig, Hossein-Ardeschir Ghofrani, Murali M. Chakinala, Joan A. Barberà, Christiana Blair, Jonathan Langley, Adaani E. Frost
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Respiratory Research
Subjects:
Pulmonary hypertension
Research-clinical
Combination therapy
Online Access:http://link.springer.com/article/10.1186/s12931-019-1180-1

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