Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Accumulating evidence indicates the occurrence and development of diabetic complications relates to not only constant high plasma glucose, but also glucose fluctuations which affect various kinds of molecular mechanisms in various target cells and tissues. In this review, we detail reactive oxygen s...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Zhen-Ye Zhang, Ling-Feng Miao, Ling-Ling Qian, Ning Wang, Miao-Miao Qi, Yu-Min Zhang, Shi-Peng Dang, Ying Wu, Ru-Xing Wang
פורמט:	Article
שפה:	English
יצא לאור:	Frontiers Media S.A. 2019-09-01
סדרה:	Frontiers in Endocrinology
נושאים:	glucose fluctuations diabetes reactive oxygen species protein kinase C protein kinase B mitogen-activated protein kinase
גישה מקוונת:	https://www.frontiersin.org/article/10.3389/fendo.2019.00640/full

פריטים דומים

Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
מאת: Cao, Jia-ning, et al.
יצא לאור: (2010)

Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt
מאת: Zhen-Ye Zhang, et al.
יצא לאור: (2024-09-01)

Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways
מאת: Dorothea Schweiger, et al.
יצא לאור: (2007-03-01)

The Solanum chacoense Fertilization-Related Kinase 3 (ScFRK3) is involved in male and female gametophyte development
מאת: Caroline Daigle, et al.
יצא לאור: (2019-05-01)

Protein Kinases as Drug Development Targets for Heart Disease Therapy
מאת: Alison L. Müller, et al.
יצא לאור: (2010-07-01)

Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways
מאת: Yu-Qin Zhao, et al.
יצא לאור: (2019-11-01)

Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway
מאת: Aisha Alhaddad, et al.
יצא לאור: (2023-03-01)

Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect
מאת: Che-Chung Yeh, et al.
יצא לאור: (2017-11-01)

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes
מאת: Kai-yuan JI, et al.
יצא לאור: (2023-04-01)

PeMPK17 interacts with PeMKK7 and participates in para-hydroxybenzoic acid stress resistance by removing reactive oxygen species
מאת: Yajie Niu, et al.
יצא לאור: (2023-09-01)

MAPK immunoreactivity in streptozotocin-induced diabetic rat testis
מאת: Yelız Bozdemır Donmez, et al.
יצא לאור: (2014-10-01)

Overexpression of SIMK in menadione-treated alfalfa enhances antioxidant machinery and leads to oxidative stress resistance
מאת: Jiří Sojka, et al.
יצא לאור: (2024-12-01)

Identification of a Spotted Leaf Sheath Gene Involved in Early Senescence and Defense Response in Rice
מאת: Dongryung Lee, et al.
יצא לאור: (2018-09-01)

ARABIDOPSIS ATMKK1 KNOCKOUT MUTANT FLOWERS UNDER SHORT DAY CONDITIONS
מאת: Chad CONROY, et al.
יצא לאור: (2024-12-01)

Remodeling tumor‐associated macrophage for anti‐cancer effects by rational design of irreversible inhibition of mitogen‐activated protein kinase‐activated protein kinase 2
מאת: Danyi Wang, et al.
יצא לאור: (2024-07-01)

Bilateral Subretinal Fluid Accumulation during Erdafitinib Therapy
מאת: Rajneesh Singh, et al.
יצא לאור: (2024-09-01)

Modulation of HERG K+ Channels by Chronic Exposure to Activators and Inhibitors of PKA and PKC: Actions Independent of PKA and PKC Phosphorylation
מאת: Liliang Shu, et al.
יצא לאור: (2013-12-01)

GmMPK6 Positively Regulates Salt Tolerance through Induction of <i>GmRbohI1</i> in Soybean
מאת: Seungmin Son, et al.
יצא לאור: (2023-02-01)

Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid
מאת: Bodil Bjørndal, et al.
יצא לאור: (2002-10-01)

Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based influenza model
מאת: Si Chen, et al.
יצא לאור: (2025-01-01)

Effects of Selenium in the MAPK Signaling Cascade
מאת: Nadereh Rashtchizadeh, et al.
יצא לאור: (2015-09-01)

Luteolin, quercetin, genistein and quercetagetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in H9c2 cardiomyoblasts
מאת: Gloria Gutiérrez-Venegas, et al.
יצא לאור: (2017-09-01)

The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
מאת: Viswanathan Saraswathi, et al.
יצא לאור: (2006-07-01)

Ceramide regulation of nuclear protein imports⃞
מאת: Randolph S. Faustino, et al.
יצא לאור: (2008-03-01)

Intermittent High Glucose Enhances the Proliferation of Rat Aortic Vascular Smooth Muscle Cells More Than Constant High Glucose via the Mitogen-Activated Protein Kinase Pathway
מאת: Sung Hoon Yu, et al.
יצא לאור: (2017-09-01)

Kinase drug discovery /
מאת: Ward, Richard A., et al.
יצא לאור: (c201)

Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients
מאת: Rafiee Mohammad, et al.
יצא לאור: (2016-07-01)

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
מאת: Sergey Filippov, et al.
יצא לאור: (2013-08-01)

Control of host cell phosphorylation by Legionella pneumophila
מאת: Eva eHaenssler, et al.
יצא לאור: (2011-04-01)

Eight Weeks of Swimming Training and CBD Oil Consumption Downregulates the Expression of MAPK and PPARα Genes in the Heart Tissue of Myocardial Infarction Rats
מאת: Ali Mohammadnia, et al.
יצא לאור: (2021-09-01)

Pharmacological implications from the adhesion-induced signaling profiles in cultured human retinal pigment epithelial cells
מאת: Wen-Chuan Wu, et al.
יצא לאור: (2014-01-01)

Losmapimod Protected Epileptic Rats From Hippocampal Neuron Damage Through Inhibition of the MAPK Pathway
מאת: Min Li, et al.
יצא לאור: (2019-06-01)

MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury
מאת: Yu B, et al.
יצא לאור: (2023-03-01)

Yomogin, Isolated from <i>Artemisia iwayomogi</i>, Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway
מאת: Jin Hee Kim, et al.
יצא לאור: (2022-12-01)

Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
מאת: Zhengqiu Zhou, et al.
יצא לאור: (2017-04-01)

The MAP Kinase Kinase Gene AbSte7 Regulates Multiple Aspects of Alternaria brassicicola Pathogenesis
מאת: Kai Lu, et al.
יצא לאור: (2019-04-01)

Function of Protein Kinases in Leaf Senescence of Plants
מאת: Fengbo Yang, et al.
יצא לאור: (2022-04-01)

Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis
מאת: Xiaoying Yao, et al.
יצא לאור: (2022-07-01)

Abl family kinases in development and disease /
מאת: Koleske, Anthony J.
יצא לאור: (2006)

Pharmacological inhibition of the MAP2K7 kinase in human disease
מאת: H. Daniel Lacorazza
יצא לאור: (2024-12-01)