Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Accumulating evidence indicates the occurrence and development of diabetic complications relates to not only constant high plasma glucose, but also glucose fluctuations which affect various kinds of molecular mechanisms in various target cells and tissues. In this review, we detail reactive oxygen s...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Zhen-Ye Zhang, Ling-Feng Miao, Ling-Ling Qian, Ning Wang, Miao-Miao Qi, Yu-Min Zhang, Shi-Peng Dang, Ying Wu, Ru-Xing Wang
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	Frontiers Media S.A. 2019-09-01
Цуврал:	Frontiers in Endocrinology
Нөхцлүүд:	glucose fluctuations diabetes reactive oxygen species protein kinase C protein kinase B mitogen-activated protein kinase
Онлайн хандалт:	https://www.frontiersin.org/article/10.3389/fendo.2019.00640/full

Ижил төстэй зүйлс

Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
-н: Cao, Jia-ning, зэрэг
Хэвлэсэн: (2010)

Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt
-н: Zhen-Ye Zhang, зэрэг
Хэвлэсэн: (2024-09-01)

Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways
-н: Dorothea Schweiger, зэрэг
Хэвлэсэн: (2007-03-01)

The Solanum chacoense Fertilization-Related Kinase 3 (ScFRK3) is involved in male and female gametophyte development
-н: Caroline Daigle, зэрэг
Хэвлэсэн: (2019-05-01)

Protein Kinases as Drug Development Targets for Heart Disease Therapy
-н: Alison L. Müller, зэрэг
Хэвлэсэн: (2010-07-01)

Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways
-н: Yu-Qin Zhao, зэрэг
Хэвлэсэн: (2019-11-01)

Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway
-н: Aisha Alhaddad, зэрэг
Хэвлэсэн: (2023-03-01)

Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect
-н: Che-Chung Yeh, зэрэг
Хэвлэсэн: (2017-11-01)

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes
-н: Kai-yuan JI, зэрэг
Хэвлэсэн: (2023-04-01)

PeMPK17 interacts with PeMKK7 and participates in para-hydroxybenzoic acid stress resistance by removing reactive oxygen species
-н: Yajie Niu, зэрэг
Хэвлэсэн: (2023-09-01)

MAPK immunoreactivity in streptozotocin-induced diabetic rat testis
-н: Yelız Bozdemır Donmez, зэрэг
Хэвлэсэн: (2014-10-01)

Overexpression of SIMK in menadione-treated alfalfa enhances antioxidant machinery and leads to oxidative stress resistance
-н: Jiří Sojka, зэрэг
Хэвлэсэн: (2024-12-01)

Identification of a Spotted Leaf Sheath Gene Involved in Early Senescence and Defense Response in Rice
-н: Dongryung Lee, зэрэг
Хэвлэсэн: (2018-09-01)

ARABIDOPSIS ATMKK1 KNOCKOUT MUTANT FLOWERS UNDER SHORT DAY CONDITIONS
-н: Chad CONROY, зэрэг
Хэвлэсэн: (2024-12-01)

Remodeling tumor‐associated macrophage for anti‐cancer effects by rational design of irreversible inhibition of mitogen‐activated protein kinase‐activated protein kinase 2
-н: Danyi Wang, зэрэг
Хэвлэсэн: (2024-07-01)

Bilateral Subretinal Fluid Accumulation during Erdafitinib Therapy
-н: Rajneesh Singh, зэрэг
Хэвлэсэн: (2024-09-01)

Modulation of HERG K+ Channels by Chronic Exposure to Activators and Inhibitors of PKA and PKC: Actions Independent of PKA and PKC Phosphorylation
-н: Liliang Shu, зэрэг
Хэвлэсэн: (2013-12-01)

GmMPK6 Positively Regulates Salt Tolerance through Induction of <i>GmRbohI1</i> in Soybean
-н: Seungmin Son, зэрэг
Хэвлэсэн: (2023-02-01)

Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid
-н: Bodil Bjørndal, зэрэг
Хэвлэсэн: (2002-10-01)

Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based influenza model
-н: Si Chen, зэрэг
Хэвлэсэн: (2025-01-01)

Effects of Selenium in the MAPK Signaling Cascade
-н: Nadereh Rashtchizadeh, зэрэг
Хэвлэсэн: (2015-09-01)

Luteolin, quercetin, genistein and quercetagetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in H9c2 cardiomyoblasts
-н: Gloria Gutiérrez-Venegas, зэрэг
Хэвлэсэн: (2017-09-01)

The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
-н: Viswanathan Saraswathi, зэрэг
Хэвлэсэн: (2006-07-01)

Ceramide regulation of nuclear protein imports⃞
-н: Randolph S. Faustino, зэрэг
Хэвлэсэн: (2008-03-01)

Intermittent High Glucose Enhances the Proliferation of Rat Aortic Vascular Smooth Muscle Cells More Than Constant High Glucose via the Mitogen-Activated Protein Kinase Pathway
-н: Sung Hoon Yu, зэрэг
Хэвлэсэн: (2017-09-01)

Kinase drug discovery /
-н: Ward, Richard A., зэрэг
Хэвлэсэн: (c201)

Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients
-н: Rafiee Mohammad, зэрэг
Хэвлэсэн: (2016-07-01)

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
-н: Sergey Filippov, зэрэг
Хэвлэсэн: (2013-08-01)

Control of host cell phosphorylation by Legionella pneumophila
-н: Eva eHaenssler, зэрэг
Хэвлэсэн: (2011-04-01)

Eight Weeks of Swimming Training and CBD Oil Consumption Downregulates the Expression of MAPK and PPARα Genes in the Heart Tissue of Myocardial Infarction Rats
-н: Ali Mohammadnia, зэрэг
Хэвлэсэн: (2021-09-01)

Pharmacological implications from the adhesion-induced signaling profiles in cultured human retinal pigment epithelial cells
-н: Wen-Chuan Wu, зэрэг
Хэвлэсэн: (2014-01-01)

Losmapimod Protected Epileptic Rats From Hippocampal Neuron Damage Through Inhibition of the MAPK Pathway
-н: Min Li, зэрэг
Хэвлэсэн: (2019-06-01)

MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury
-н: Yu B, зэрэг
Хэвлэсэн: (2023-03-01)

Yomogin, Isolated from <i>Artemisia iwayomogi</i>, Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway
-н: Jin Hee Kim, зэрэг
Хэвлэсэн: (2022-12-01)

Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
-н: Zhengqiu Zhou, зэрэг
Хэвлэсэн: (2017-04-01)

The MAP Kinase Kinase Gene AbSte7 Regulates Multiple Aspects of Alternaria brassicicola Pathogenesis
-н: Kai Lu, зэрэг
Хэвлэсэн: (2019-04-01)

Function of Protein Kinases in Leaf Senescence of Plants
-н: Fengbo Yang, зэрэг
Хэвлэсэн: (2022-04-01)

Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis
-н: Xiaoying Yao, зэрэг
Хэвлэсэн: (2022-07-01)

Abl family kinases in development and disease /
-н: Koleske, Anthony J.
Хэвлэсэн: (2006)

Pharmacological inhibition of the MAP2K7 kinase in human disease
-н: H. Daniel Lacorazza
Хэвлэсэн: (2024-12-01)