Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Molecular Mechanisms of Glucose Fluctuations on Diabetic Complications

Accumulating evidence indicates the occurrence and development of diabetic complications relates to not only constant high plasma glucose, but also glucose fluctuations which affect various kinds of molecular mechanisms in various target cells and tissues. In this review, we detail reactive oxygen s...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Zhen-Ye Zhang, Ling-Feng Miao, Ling-Ling Qian, Ning Wang, Miao-Miao Qi, Yu-Min Zhang, Shi-Peng Dang, Ying Wu, Ru-Xing Wang
Formaat:	Artikel
Taal:	English
Gepubliceerd in:	Frontiers Media S.A. 2019-09-01
Reeks:	Frontiers in Endocrinology
Onderwerpen:	glucose fluctuations diabetes reactive oxygen species protein kinase C protein kinase B mitogen-activated protein kinase
Online toegang:	https://www.frontiersin.org/article/10.3389/fendo.2019.00640/full

Gelijkaardige items

Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
door: Cao, Jia-ning, et al.
Gepubliceerd in: (2010)

Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt
door: Zhen-Ye Zhang, et al.
Gepubliceerd in: (2024-09-01)

Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways
door: Dorothea Schweiger, et al.
Gepubliceerd in: (2007-03-01)

The Solanum chacoense Fertilization-Related Kinase 3 (ScFRK3) is involved in male and female gametophyte development
door: Caroline Daigle, et al.
Gepubliceerd in: (2019-05-01)

Protein Kinases as Drug Development Targets for Heart Disease Therapy
door: Alison L. Müller, et al.
Gepubliceerd in: (2010-07-01)

Fucoxanthin attenuates doxorubicin-induced cardiotoxicity via anti-oxidant and anti-apoptotic mechanisms associated with p38, JNK and p53 pathways
door: Yu-Qin Zhao, et al.
Gepubliceerd in: (2019-11-01)

Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway
door: Aisha Alhaddad, et al.
Gepubliceerd in: (2023-03-01)

Atrial ERK1/2 activation in the embryo leads to incomplete Septal closure: a novel mouse model of atrial Septal defect
door: Che-Chung Yeh, et al.
Gepubliceerd in: (2017-11-01)

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes
door: Kai-yuan JI, et al.
Gepubliceerd in: (2023-04-01)

PeMPK17 interacts with PeMKK7 and participates in para-hydroxybenzoic acid stress resistance by removing reactive oxygen species
door: Yajie Niu, et al.
Gepubliceerd in: (2023-09-01)

MAPK immunoreactivity in streptozotocin-induced diabetic rat testis
door: Yelız Bozdemır Donmez, et al.
Gepubliceerd in: (2014-10-01)

Overexpression of SIMK in menadione-treated alfalfa enhances antioxidant machinery and leads to oxidative stress resistance
door: Jiří Sojka, et al.
Gepubliceerd in: (2024-12-01)

Identification of a Spotted Leaf Sheath Gene Involved in Early Senescence and Defense Response in Rice
door: Dongryung Lee, et al.
Gepubliceerd in: (2018-09-01)

ARABIDOPSIS ATMKK1 KNOCKOUT MUTANT FLOWERS UNDER SHORT DAY CONDITIONS
door: Chad CONROY, et al.
Gepubliceerd in: (2024-12-01)

Remodeling tumor‐associated macrophage for anti‐cancer effects by rational design of irreversible inhibition of mitogen‐activated protein kinase‐activated protein kinase 2
door: Danyi Wang, et al.
Gepubliceerd in: (2024-07-01)

Bilateral Subretinal Fluid Accumulation during Erdafitinib Therapy
door: Rajneesh Singh, et al.
Gepubliceerd in: (2024-09-01)

Modulation of HERG K+ Channels by Chronic Exposure to Activators and Inhibitors of PKA and PKC: Actions Independent of PKA and PKC Phosphorylation
door: Liliang Shu, et al.
Gepubliceerd in: (2013-12-01)

GmMPK6 Positively Regulates Salt Tolerance through Induction of <i>GmRbohI1</i> in Soybean
door: Seungmin Son, et al.
Gepubliceerd in: (2023-02-01)

Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid
door: Bodil Bjørndal, et al.
Gepubliceerd in: (2002-10-01)

Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based influenza model
door: Si Chen, et al.
Gepubliceerd in: (2025-01-01)

Effects of Selenium in the MAPK Signaling Cascade
door: Nadereh Rashtchizadeh, et al.
Gepubliceerd in: (2015-09-01)

Luteolin, quercetin, genistein and quercetagetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in H9c2 cardiomyoblasts
door: Gloria Gutiérrez-Venegas, et al.
Gepubliceerd in: (2017-09-01)

The role of lipolysis in mediating the proinflammatory effects of very low density lipoproteins in mouse peritoneal macrophages
door: Viswanathan Saraswathi, et al.
Gepubliceerd in: (2006-07-01)

Ceramide regulation of nuclear protein imports⃞
door: Randolph S. Faustino, et al.
Gepubliceerd in: (2008-03-01)

Intermittent High Glucose Enhances the Proliferation of Rat Aortic Vascular Smooth Muscle Cells More Than Constant High Glucose via the Mitogen-Activated Protein Kinase Pathway
door: Sung Hoon Yu, et al.
Gepubliceerd in: (2017-09-01)

Kinase drug discovery /
door: Ward, Richard A., et al.
Gepubliceerd in: (c201)

Down-Regulation of Ribosomal S6 kinase RPS6KA6 in Acute Myeloid Leukemia Patients
door: Rafiee Mohammad, et al.
Gepubliceerd in: (2016-07-01)

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK
door: Sergey Filippov, et al.
Gepubliceerd in: (2013-08-01)

Control of host cell phosphorylation by Legionella pneumophila
door: Eva eHaenssler, et al.
Gepubliceerd in: (2011-04-01)

Eight Weeks of Swimming Training and CBD Oil Consumption Downregulates the Expression of MAPK and PPARα Genes in the Heart Tissue of Myocardial Infarction Rats
door: Ali Mohammadnia, et al.
Gepubliceerd in: (2021-09-01)

Pharmacological implications from the adhesion-induced signaling profiles in cultured human retinal pigment epithelial cells
door: Wen-Chuan Wu, et al.
Gepubliceerd in: (2014-01-01)

Losmapimod Protected Epileptic Rats From Hippocampal Neuron Damage Through Inhibition of the MAPK Pathway
door: Min Li, et al.
Gepubliceerd in: (2019-06-01)

MAPK Signaling Pathways in Hepatic Ischemia/Reperfusion Injury
door: Yu B, et al.
Gepubliceerd in: (2023-03-01)

Yomogin, Isolated from <i>Artemisia iwayomogi</i>, Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway
door: Jin Hee Kim, et al.
Gepubliceerd in: (2022-12-01)

Retention of normal glia function by an isoform-selective protein kinase inhibitor drug candidate that modulates cytokine production and cognitive outcomes
door: Zhengqiu Zhou, et al.
Gepubliceerd in: (2017-04-01)

The MAP Kinase Kinase Gene AbSte7 Regulates Multiple Aspects of Alternaria brassicicola Pathogenesis
door: Kai Lu, et al.
Gepubliceerd in: (2019-04-01)

Function of Protein Kinases in Leaf Senescence of Plants
door: Fengbo Yang, et al.
Gepubliceerd in: (2022-04-01)

Inducible nitric oxide synthase regulates macrophage polarization via the MAPK signals in concanavalin A‐induced hepatitis
door: Xiaoying Yao, et al.
Gepubliceerd in: (2022-07-01)

Abl family kinases in development and disease /
door: Koleske, Anthony J.
Gepubliceerd in: (2006)

Pharmacological inhibition of the MAP2K7 kinase in human disease
door: H. Daniel Lacorazza
Gepubliceerd in: (2024-12-01)