Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder
Abstract Purpose The Autism Behavior Inventory (ABI) is an observer-reported outcome scale measuring core and associated features of autism spectrum disorder (ASD). Extensive scale development (reported elsewhere) took place, in alignment with the Food and Drug Administration’s patient-reported outc...
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| Format: | Article |
| Language: | English |
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BMC
2021-01-01
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| Series: | Health and Quality of Life Outcomes |
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| Online Access: | https://doi.org/10.1186/s12955-020-01665-w |
| _version_ | 1818393443819323392 |
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| author | Gahan Pandina Seth Ness Jeremiah Trudeau Sonja Stringer Naomi Knoble William R. Lenderking Abigail Bangerter |
| author_facet | Gahan Pandina Seth Ness Jeremiah Trudeau Sonja Stringer Naomi Knoble William R. Lenderking Abigail Bangerter |
| author_sort | Gahan Pandina |
| collection | DOAJ |
| description | Abstract Purpose The Autism Behavior Inventory (ABI) is an observer-reported outcome scale measuring core and associated features of autism spectrum disorder (ASD). Extensive scale development (reported elsewhere) took place, in alignment with the Food and Drug Administration’s patient-reported outcome guidance, to address the need for instruments to measure change and severity of ASD symptoms. Methods Cognitive interviewing was used to confirm understanding and content validity of the scale prior to its use in clinical trials. Respondents were caregivers of individuals with ASD (N = 50). Interviews used a hybrid of the “think-aloud” and verbal probing approach to assess ABI’s content validity and participant understanding of the instrument, including: item clarity and relevance; item interpretation; appropriateness of response scales; and clarity of instructions. Audio-recordings of the interviews were transcribed for qualitative data analysis. The scale was revised based on participant feedback and tested in a second round of interviews (round 1 N = 38, round 2 N = 12). Results In total, 67/70 items reached ≥ 90% understandability across participants. Caregivers were able to select an appropriate response from the options available and reported finding the examples helpful. Based on participant feedback, instructions were simplified, 8 items were removed, and 10 items were reworded. The final revised 62-item scale was presented in round 2, where caregivers reported readily understanding the instructions, response options, and 61/62 items reached ≥ 90% understandability. Conclusions Cognitive interviews with caregivers of a diverse sample of individuals with ASD confirm the content validity and relevance of the ABI to assess core and associated symptoms of ASD. |
| first_indexed | 2024-12-14T05:45:24Z |
| format | Article |
| id | doaj.art-f45b64f8a6ea4deab785a528f7fd5f7d |
| institution | Directory Open Access Journal |
| issn | 1477-7525 |
| language | English |
| last_indexed | 2024-12-14T05:45:24Z |
| publishDate | 2021-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Health and Quality of Life Outcomes |
| spelling | doaj.art-f45b64f8a6ea4deab785a528f7fd5f7d2022-12-21T23:14:53ZengBMCHealth and Quality of Life Outcomes1477-75252021-01-0119111310.1186/s12955-020-01665-wQualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorderGahan Pandina0Seth Ness1Jeremiah Trudeau2Sonja Stringer3Naomi Knoble4William R. Lenderking5Abigail Bangerter6Department of Neuroscience, Janssen Research & Development, LLCDepartment of Neuroscience, Janssen Research & Development, LLCDepartment of Patient Reported Outcomes, Janssen Global ServicesEvidera, Pharmaceutical Product Development, LLCEvidera, Pharmaceutical Product Development, LLCEvidera, Pharmaceutical Product Development, LLCDepartment of Neuroscience, Janssen Research & Development, LLCAbstract Purpose The Autism Behavior Inventory (ABI) is an observer-reported outcome scale measuring core and associated features of autism spectrum disorder (ASD). Extensive scale development (reported elsewhere) took place, in alignment with the Food and Drug Administration’s patient-reported outcome guidance, to address the need for instruments to measure change and severity of ASD symptoms. Methods Cognitive interviewing was used to confirm understanding and content validity of the scale prior to its use in clinical trials. Respondents were caregivers of individuals with ASD (N = 50). Interviews used a hybrid of the “think-aloud” and verbal probing approach to assess ABI’s content validity and participant understanding of the instrument, including: item clarity and relevance; item interpretation; appropriateness of response scales; and clarity of instructions. Audio-recordings of the interviews were transcribed for qualitative data analysis. The scale was revised based on participant feedback and tested in a second round of interviews (round 1 N = 38, round 2 N = 12). Results In total, 67/70 items reached ≥ 90% understandability across participants. Caregivers were able to select an appropriate response from the options available and reported finding the examples helpful. Based on participant feedback, instructions were simplified, 8 items were removed, and 10 items were reworded. The final revised 62-item scale was presented in round 2, where caregivers reported readily understanding the instructions, response options, and 61/62 items reached ≥ 90% understandability. Conclusions Cognitive interviews with caregivers of a diverse sample of individuals with ASD confirm the content validity and relevance of the ABI to assess core and associated symptoms of ASD.https://doi.org/10.1186/s12955-020-01665-wAutismCognitive interviewCaregiver-reported outcomes |
| spellingShingle | Gahan Pandina Seth Ness Jeremiah Trudeau Sonja Stringer Naomi Knoble William R. Lenderking Abigail Bangerter Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder Health and Quality of Life Outcomes Autism Cognitive interview Caregiver-reported outcomes |
| title | Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder |
| title_full | Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder |
| title_fullStr | Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder |
| title_full_unstemmed | Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder |
| title_short | Qualitative evaluation of the Autism Behavior Inventory: use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder |
| title_sort | qualitative evaluation of the autism behavior inventory use of cognitive interviewing to establish validity of a caregiver report scale for autism spectrum disorder |
| topic | Autism Cognitive interview Caregiver-reported outcomes |
| url | https://doi.org/10.1186/s12955-020-01665-w |
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