Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The seru...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2021-07-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2021-0315 |
| _version_ | 1811202979139682304 |
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| author | Wan Yan Jiang Guoqing Jin Ying Hao Zengping |
| author_facet | Wan Yan Jiang Guoqing Jin Ying Hao Zengping |
| author_sort | Wan Yan |
| collection | DOAJ |
| description | Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The serum human chorionic gonadotropin (HCG) level ranged from 944 to 1,286 mIU/mL before treatments. The signs of preeclampsia and hyperthyroidism were relatively prominent. Hysterectomy was performed and chemotherapy was scheduled when the serum HCG level remained at a plateau, about 528 mIU/mL. The symptoms of preeclampsia and hyperthyroidism were relieved after treatment. Accordingly, we concluded that GTD could occur in perimenopausal woman and hysterectomy usually is the optimal treatment. |
| first_indexed | 2024-04-12T02:47:01Z |
| format | Article |
| id | doaj.art-f45c1848c1684d518311004a4441915a |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-04-12T02:47:01Z |
| publishDate | 2021-07-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-f45c1848c1684d518311004a4441915a2022-12-22T03:51:08ZengDe GruyterOpen Medicine2391-54632021-07-011611038104210.1515/med-2021-0315Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature reviewWan Yan0Jiang Guoqing1Jin Ying2Hao Zengping3Department of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, ChinaDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Tsinghua University, Beijing 100016, ChinaDepartment of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, ChinaDepartment of Obstetrics and Gynecology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, ChinaGestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The serum human chorionic gonadotropin (HCG) level ranged from 944 to 1,286 mIU/mL before treatments. The signs of preeclampsia and hyperthyroidism were relatively prominent. Hysterectomy was performed and chemotherapy was scheduled when the serum HCG level remained at a plateau, about 528 mIU/mL. The symptoms of preeclampsia and hyperthyroidism were relieved after treatment. Accordingly, we concluded that GTD could occur in perimenopausal woman and hysterectomy usually is the optimal treatment.https://doi.org/10.1515/med-2021-0315giant hydatidiform moleperimenopausalpreeclampsiahyperthyroidism |
| spellingShingle | Wan Yan Jiang Guoqing Jin Ying Hao Zengping Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review Open Medicine giant hydatidiform mole perimenopausal preeclampsia hyperthyroidism |
| title | Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review |
| title_full | Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review |
| title_fullStr | Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review |
| title_full_unstemmed | Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review |
| title_short | Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review |
| title_sort | perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism a case report and literature review |
| topic | giant hydatidiform mole perimenopausal preeclampsia hyperthyroidism |
| url | https://doi.org/10.1515/med-2021-0315 |
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