Improved influenza vaccine responses after expression of multiple viral glycoproteins from a single mRNA

Abstract Influenza viruses cause substantial morbidity and mortality every year despite seasonal vaccination. mRNA-based vaccines have the potential to elicit more protective immune responses, but for maximal breadth and durability, it is desirable to deliver both the viral hemagglutinin and neurami...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Rebecca A. Leonard, Kaitlyn N. Burke, Rachel L. Spreng, Andrew N. Macintyre, Ying Tam, Mohamad-Gabriel Alameh, Drew Weissman, Nicholas S. Heaton
التنسيق: مقال
اللغة:English
منشور في: Nature Portfolio 2024-10-01
سلاسل:Nature Communications
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-024-52940-z