Improved influenza vaccine responses after expression of multiple viral glycoproteins from a single mRNA
Abstract Influenza viruses cause substantial morbidity and mortality every year despite seasonal vaccination. mRNA-based vaccines have the potential to elicit more protective immune responses, but for maximal breadth and durability, it is desirable to deliver both the viral hemagglutinin and neurami...
Principais autores: | , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Nature Portfolio
2024-10-01
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coleção: | Nature Communications |
Acesso em linha: | https://doi.org/10.1038/s41467-024-52940-z |