Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth
The objective of this study was to determine the gamma-glutamyl transferase (GGT) levels and its relationship with diarrhea and passive transfer of immunity in Holstein calves within 24 hours and 30 days of life from Leopolis municipality, the north Parana region. Colostrum is rich in immunoglobulin...
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| Format: | Article |
| Language: | English |
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Universidade Federal de Uberlândia
2016-04-01
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| Series: | Bioscience Journal |
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| Online Access: | http://www.seer.ufu.br/index.php/biosciencejournal/article/view/29476 |
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| author | Luiz Carlos Negri Filho Célio Eduardo Sargentin Pereira Pedro Herique Newbery Chineze Alexey Leon Gomel Bogado Dalton Evert Bronkhorst Michele Lunardi Werner Okano |
| author_facet | Luiz Carlos Negri Filho Célio Eduardo Sargentin Pereira Pedro Herique Newbery Chineze Alexey Leon Gomel Bogado Dalton Evert Bronkhorst Michele Lunardi Werner Okano |
| author_sort | Luiz Carlos Negri Filho |
| collection | DOAJ |
| description | The objective of this study was to determine the gamma-glutamyl transferase (GGT) levels and its relationship with diarrhea and passive transfer of immunity in Holstein calves within 24 hours and 30 days of life from Leopolis municipality, the north Parana region. Colostrum is rich in immunoglobulins and vital for immunity to newborn calves, since bovine placenta does not allow the passage of immunoglobulin to the fetus. Calves undergo various challenges that can lead to disease and death in the first month of life, including diarrhea. Diarrhea has a multifactorial etiology, and the passive immunity transferred through ingestion of colostrum is able to protect the calf against many of these etiologic agents. GGT measurements indirectly infer the amount of immunoglobulin ingested by the calf. Higher serum GGT levels (381.72 IU / L) were found at 24 hours, and a significant reduction was observed at 30 days (66.22 IU / L). When the presence or absence of diarrhea was associated with GGT levels above and below 200 IU / L, no statistical significance (P> 0.05) was observed, since 80% of animals with diarrhea had serum GGT levels higher than 200 IU / L. Under the conditions of this study, there was no relationship between the GGT concentration and the occurrence of diarrhea, and no mortality was observed despite some animals presented diarrhea. |
| first_indexed | 2024-12-18T02:14:05Z |
| format | Article |
| id | doaj.art-f45cdcd294704647bfe7d4870b92b056 |
| institution | Directory Open Access Journal |
| issn | 1981-3163 |
| language | English |
| last_indexed | 2024-12-18T02:14:05Z |
| publishDate | 2016-04-01 |
| publisher | Universidade Federal de Uberlândia |
| record_format | Article |
| series | Bioscience Journal |
| spelling | doaj.art-f45cdcd294704647bfe7d4870b92b0562022-12-21T21:24:25ZengUniversidade Federal de UberlândiaBioscience Journal1981-31632016-04-0132210.14393/BJ-v32n2a2016-2947629476Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birthLuiz Carlos Negri Filho0Célio Eduardo Sargentin Pereira1Pedro Herique Newbery Chineze2Alexey Leon Gomel Bogado3Dalton Evert Bronkhorst4Michele Lunardi5Werner Okano6Medicina Veterinária Universidade Norte do Paraná (UNOPAR)Medicina Veterinária Universidade Norte do Paraná (UNOPAR)Medicina Veterinária Universidade Norte do Paraná (UNOPAR)Medicina Veterinária Universidade Norte do Paraná (UNOPAR)Medicina Veterinária Universidade Norte do Paraná (UNOPAR)Universidade de Cuiabá (UNIC)Medicina Veterinária Universidade Norte do Paraná (UNOPAR)The objective of this study was to determine the gamma-glutamyl transferase (GGT) levels and its relationship with diarrhea and passive transfer of immunity in Holstein calves within 24 hours and 30 days of life from Leopolis municipality, the north Parana region. Colostrum is rich in immunoglobulins and vital for immunity to newborn calves, since bovine placenta does not allow the passage of immunoglobulin to the fetus. Calves undergo various challenges that can lead to disease and death in the first month of life, including diarrhea. Diarrhea has a multifactorial etiology, and the passive immunity transferred through ingestion of colostrum is able to protect the calf against many of these etiologic agents. GGT measurements indirectly infer the amount of immunoglobulin ingested by the calf. Higher serum GGT levels (381.72 IU / L) were found at 24 hours, and a significant reduction was observed at 30 days (66.22 IU / L). When the presence or absence of diarrhea was associated with GGT levels above and below 200 IU / L, no statistical significance (P> 0.05) was observed, since 80% of animals with diarrhea had serum GGT levels higher than 200 IU / L. Under the conditions of this study, there was no relationship between the GGT concentration and the occurrence of diarrhea, and no mortality was observed despite some animals presented diarrhea.http://www.seer.ufu.br/index.php/biosciencejournal/article/view/29476passive immunity. newborn calves. gamma-glutamyl transferase. colostrum. |
| spellingShingle | Luiz Carlos Negri Filho Célio Eduardo Sargentin Pereira Pedro Herique Newbery Chineze Alexey Leon Gomel Bogado Dalton Evert Bronkhorst Michele Lunardi Werner Okano Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth Bioscience Journal passive immunity. newborn calves. gamma-glutamyl transferase. colostrum. |
| title | Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth |
| title_full | Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth |
| title_fullStr | Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth |
| title_full_unstemmed | Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth |
| title_short | Use of the enzyme gamma-glutamyl transferase (GGT) as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth |
| title_sort | use of the enzyme gamma glutamyl transferase ggt as an indirect measure of passive transfer of immunity in holstein calves and association with the occurrence of diarrhea after birth |
| topic | passive immunity. newborn calves. gamma-glutamyl transferase. colostrum. |
| url | http://www.seer.ufu.br/index.php/biosciencejournal/article/view/29476 |
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