High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report
Multiple primary malignant neoplasms are a rare gynecologic malignancy; particularly, cases originating from the heterologous organs, such as the ovary and cervix. Here, we report a case of two primary malignant neoplasms in a patient who had undergone laparoscopic radical hysterectomy + bilateral s...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2024.1298109/full |
| _version_ | 1797270180404920320 |
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| author | Maoyuan Wu Wenwen Zhang Lianli He Ye Zhu Xiaoling Jiang Lixia Zhang Xiwei Yuan Tingchao Li |
| author_facet | Maoyuan Wu Wenwen Zhang Lianli He Ye Zhu Xiaoling Jiang Lixia Zhang Xiwei Yuan Tingchao Li |
| author_sort | Maoyuan Wu |
| collection | DOAJ |
| description | Multiple primary malignant neoplasms are a rare gynecologic malignancy; particularly, cases originating from the heterologous organs, such as the ovary and cervix. Here, we report a case of two primary malignant neoplasms in a patient who had undergone laparoscopic radical hysterectomy + bilateral salpingo-oophorectomy + pelvic lymph node dissection + para-aortic lymphadenectomy + appendectomy + omentectomy + metastasectomy under general anesthesia. The patient experienced complete remission after six courses of postoperative chemotherapy with a standard Taxol and Carboplatin regimen. Genetic testing was performed to detect BRCA2 mutations, and poly (ADP-ribose) polymerase (PARP) inhibitors were used for maintenance therapy. |
| first_indexed | 2024-04-25T02:00:10Z |
| format | Article |
| id | doaj.art-f45cf2b4899644a1abff8b514a1e7726 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-25T02:00:10Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-f45cf2b4899644a1abff8b514a1e77262024-03-07T15:13:59ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-03-011410.3389/fonc.2024.12981091298109High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case reportMaoyuan Wu0Wenwen Zhang1Lianli He2Ye Zhu3Xiaoling Jiang4Lixia Zhang5Xiwei Yuan6Tingchao Li7Department of Gynecology and Obstetrics, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, Guizhou, ChinaDepartment of Gynecology and Obstetrics, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, Guizhou, ChinaDepartment of Gynecology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, Guizhou, ChinaDepartment of Gynecology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, Guizhou, ChinaDepartment of Gynecology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, Guizhou, ChinaDepartment of Gynecology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, Guizhou, ChinaDepartment of Imaging, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaDepartment of Pathology, The Third Affiliated Hospital of Zunyi Medical University (The First People’s Hospital of Zunyi), Zunyi, ChinaMultiple primary malignant neoplasms are a rare gynecologic malignancy; particularly, cases originating from the heterologous organs, such as the ovary and cervix. Here, we report a case of two primary malignant neoplasms in a patient who had undergone laparoscopic radical hysterectomy + bilateral salpingo-oophorectomy + pelvic lymph node dissection + para-aortic lymphadenectomy + appendectomy + omentectomy + metastasectomy under general anesthesia. The patient experienced complete remission after six courses of postoperative chemotherapy with a standard Taxol and Carboplatin regimen. Genetic testing was performed to detect BRCA2 mutations, and poly (ADP-ribose) polymerase (PARP) inhibitors were used for maintenance therapy.https://www.frontiersin.org/articles/10.3389/fonc.2024.1298109/fullcase reportmultiple primary malignant neoplasmscervical cancerovarian cancerhigh-grade serous papillary carcinoma |
| spellingShingle | Maoyuan Wu Wenwen Zhang Lianli He Ye Zhu Xiaoling Jiang Lixia Zhang Xiwei Yuan Tingchao Li High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report Frontiers in Oncology case report multiple primary malignant neoplasms cervical cancer ovarian cancer high-grade serous papillary carcinoma |
| title | High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report |
| title_full | High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report |
| title_fullStr | High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report |
| title_full_unstemmed | High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report |
| title_short | High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report |
| title_sort | high grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix a case report |
| topic | case report multiple primary malignant neoplasms cervical cancer ovarian cancer high-grade serous papillary carcinoma |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2024.1298109/full |
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