The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi
<p>Abstract</p> <p>In this review we will focus on the current status and views concerning the production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi. We will focus on single-chain antibody fragment production (scFv and V<sub>HH</sub&...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2003-01-01
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| Series: | Microbial Cell Factories |
| Online Access: | http://www.microbialcellfactories.com/content/2/1/1 |
| _version_ | 1818526540658376704 |
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| author | van den Hondel Cees AMJJ Lokman Christien Joosten Vivi Punt Peter J |
| author_facet | van den Hondel Cees AMJJ Lokman Christien Joosten Vivi Punt Peter J |
| author_sort | van den Hondel Cees AMJJ |
| collection | DOAJ |
| description | <p>Abstract</p> <p>In this review we will focus on the current status and views concerning the production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi. We will focus on single-chain antibody fragment production (scFv and V<sub>HH</sub>) by these lower eukaryotes and the possible applications of these proteins. Also the coupling of fragments to relevant enzymes or other components will be discussed. As an example of the fusion protein strategy, the 'magic bullet' approach for industrial applications, will be highlighted.</p> |
| first_indexed | 2024-12-11T06:24:22Z |
| format | Article |
| id | doaj.art-f46280a88f324833923a0f1ee21cca7e |
| institution | Directory Open Access Journal |
| issn | 1475-2859 |
| language | English |
| last_indexed | 2024-12-11T06:24:22Z |
| publishDate | 2003-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Microbial Cell Factories |
| spelling | doaj.art-f46280a88f324833923a0f1ee21cca7e2022-12-22T01:17:43ZengBMCMicrobial Cell Factories1475-28592003-01-0121110.1186/1475-2859-2-1The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungivan den Hondel Cees AMJJLokman ChristienJoosten ViviPunt Peter J<p>Abstract</p> <p>In this review we will focus on the current status and views concerning the production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi. We will focus on single-chain antibody fragment production (scFv and V<sub>HH</sub>) by these lower eukaryotes and the possible applications of these proteins. Also the coupling of fragments to relevant enzymes or other components will be discussed. As an example of the fusion protein strategy, the 'magic bullet' approach for industrial applications, will be highlighted.</p>http://www.microbialcellfactories.com/content/2/1/1 |
| spellingShingle | van den Hondel Cees AMJJ Lokman Christien Joosten Vivi Punt Peter J The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi Microbial Cell Factories |
| title | The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi |
| title_full | The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi |
| title_fullStr | The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi |
| title_full_unstemmed | The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi |
| title_short | The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi |
| title_sort | production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi |
| url | http://www.microbialcellfactories.com/content/2/1/1 |
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