Short-Term Effects of Botulinum Toxin-A Injection on the Medial Gastrocnemius Histological Features in Ambulant Children with Cerebral Palsy: A Longitudinal Pilot Study

Short-Term Effects of Botulinum Toxin-A Injection on the Medial Gastrocnemius Histological Features in Ambulant Children with Cerebral Palsy: A Longitudinal Pilot Study

Botulinum toxin-A (BoNT-A) injection is known to exert beneficial effects on muscle tone, joint mobility and gait in children with cerebral palsy (CP). However, recent animal and human studies have raised the concern that BoNT-A might be harmful to muscle integrity. In CP-children, the impact of BoN...

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Bibliographic Details
Main Authors: Jorieke Deschrevel, Anke Andries, Karen Maes, Nathalie De Beukelaer, Marlies Corvelyn, Lauraine Staut, Hannah De Houwer, Domiziana Costamagna, Kaat Desloovere, Anja Van Campenhout, Ghislaine Gayan-Ramirez
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Toxins
Subjects:
microbiopsy
myosin heavy chain
spasticity
muscle fiber size
muscle fiber proportion
satellite cells
Online Access:https://www.mdpi.com/2072-6651/16/2/69

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