Allergic reaction to patent blue dye in breast surgery - case report

Abstract We present a case of allergic reaction to patent blue in a patient who underwent excision of sentinel lymph node associated with segmental breast resection. About 20 min after the dye injection, the patient developed hypotension (BP = 70 × 30 mmHg) associated with increased heart frequency....

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Main Authors: Marcius Vinícius M. Maranhão, Dyluzia Kelly Amaral da Nóbrega, Carlos Eduardo Caiado Anunciação, Barbara de Alcântara Brito Maia, Paulo Virgílio Dantas Mariano
Format: Article
Language:English
Published: Sociedade Brasileira de Anestesiologia 2016-08-01
Series:Revista Brasileira de Anestesiologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000400433&lng=en&tlng=en
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author Marcius Vinícius M. Maranhão
Dyluzia Kelly Amaral da Nóbrega
Carlos Eduardo Caiado Anunciação
Barbara de Alcântara Brito Maia
Paulo Virgílio Dantas Mariano
author_facet Marcius Vinícius M. Maranhão
Dyluzia Kelly Amaral da Nóbrega
Carlos Eduardo Caiado Anunciação
Barbara de Alcântara Brito Maia
Paulo Virgílio Dantas Mariano
author_sort Marcius Vinícius M. Maranhão
collection DOAJ
description Abstract We present a case of allergic reaction to patent blue in a patient who underwent excision of sentinel lymph node associated with segmental breast resection. About 20 min after the dye injection, the patient developed hypotension (BP = 70 × 30 mmHg) associated with increased heart frequency. The patient was treated successfully with decreased inspired fraction of inhaled anesthetic and fluid replacement. At the end of the procedure, she presented with bluish urticarial-like plaques on the head, neck, upper limbs, and trunk; hydrocortisone was then used. The patient recovered uneventfully and was discharged from the PACU 2 h after the end of surgery without skin changes, and was discharged from hospital on the morning after surgery. The incidence of allergic reactions with the use of patent blue is far superior to the hypersensitivity reactions seen with anesthetic and adjuvant drugs. Therefore, the anesthesiologist must be aware of cardiovascular instability associated with skin changes during the use of patent blue, for early diagnosis and appropriate treatment of this hypersensitivity reaction to this dye.
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spelling doaj.art-f4675b5cae7a4b5ea391a0268babb9872022-12-22T03:20:51ZengSociedade Brasileira de AnestesiologiaRevista Brasileira de Anestesiologia1806-907X2016-08-0166443343610.1016/j.bjane.2014.02.018S0034-70942016000400433Allergic reaction to patent blue dye in breast surgery - case reportMarcius Vinícius M. MaranhãoDyluzia Kelly Amaral da NóbregaCarlos Eduardo Caiado AnunciaçãoBarbara de Alcântara Brito MaiaPaulo Virgílio Dantas MarianoAbstract We present a case of allergic reaction to patent blue in a patient who underwent excision of sentinel lymph node associated with segmental breast resection. About 20 min after the dye injection, the patient developed hypotension (BP = 70 × 30 mmHg) associated with increased heart frequency. The patient was treated successfully with decreased inspired fraction of inhaled anesthetic and fluid replacement. At the end of the procedure, she presented with bluish urticarial-like plaques on the head, neck, upper limbs, and trunk; hydrocortisone was then used. The patient recovered uneventfully and was discharged from the PACU 2 h after the end of surgery without skin changes, and was discharged from hospital on the morning after surgery. The incidence of allergic reactions with the use of patent blue is far superior to the hypersensitivity reactions seen with anesthetic and adjuvant drugs. Therefore, the anesthesiologist must be aware of cardiovascular instability associated with skin changes during the use of patent blue, for early diagnosis and appropriate treatment of this hypersensitivity reaction to this dye.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000400433&lng=en&tlng=enAnestesiaAnafilaxiaHipersensibilidadeAzul patente
spellingShingle Marcius Vinícius M. Maranhão
Dyluzia Kelly Amaral da Nóbrega
Carlos Eduardo Caiado Anunciação
Barbara de Alcântara Brito Maia
Paulo Virgílio Dantas Mariano
Allergic reaction to patent blue dye in breast surgery - case report
Revista Brasileira de Anestesiologia
Anestesia
Anafilaxia
Hipersensibilidade
Azul patente
title Allergic reaction to patent blue dye in breast surgery - case report
title_full Allergic reaction to patent blue dye in breast surgery - case report
title_fullStr Allergic reaction to patent blue dye in breast surgery - case report
title_full_unstemmed Allergic reaction to patent blue dye in breast surgery - case report
title_short Allergic reaction to patent blue dye in breast surgery - case report
title_sort allergic reaction to patent blue dye in breast surgery case report
topic Anestesia
Anafilaxia
Hipersensibilidade
Azul patente
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942016000400433&lng=en&tlng=en
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