Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications
Anthrax toxins are produced by <i>Bacillus anthracis</i> throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient. They have thus been long ignored, but recent biochemical methods have improved our knowledge in ani...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/8/8/1103 |
| _version_ | 1827712560324935680 |
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| author | Jean-Nicolas Tournier Clémence Rougeaux |
| author_facet | Jean-Nicolas Tournier Clémence Rougeaux |
| author_sort | Jean-Nicolas Tournier |
| collection | DOAJ |
| description | Anthrax toxins are produced by <i>Bacillus anthracis</i> throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient. They have thus been long ignored, but recent biochemical methods have improved our knowledge in animal models. This article reviews the various methods that have been used and how they could be applied to clinical diagnosis. |
| first_indexed | 2024-03-10T18:16:30Z |
| format | Article |
| id | doaj.art-f4697ef6eca64579a069bcedf7d4861b |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T18:16:30Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-f4697ef6eca64579a069bcedf7d4861b2023-11-20T07:42:34ZengMDPI AGMicroorganisms2076-26072020-07-0188110310.3390/microorganisms8081103Anthrax Toxin Detection: From In Vivo Studies to Diagnostic ApplicationsJean-Nicolas Tournier0Clémence Rougeaux1Unité Bactériologie Biothérapies Anti-infectieuses et Immunité, Institut de Recherche Biomédicale des Armées (IRBA), 1 place Général Valérie André, 91220 Brétigny sur Orge, FranceUnité Bactériologie Biothérapies Anti-infectieuses et Immunité, Institut de Recherche Biomédicale des Armées (IRBA), 1 place Général Valérie André, 91220 Brétigny sur Orge, FranceAnthrax toxins are produced by <i>Bacillus anthracis</i> throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient. They have thus been long ignored, but recent biochemical methods have improved our knowledge in animal models. This article reviews the various methods that have been used and how they could be applied to clinical diagnosis.https://www.mdpi.com/2076-2607/8/8/1103anthraxtoxinslethal factoredema factorprotective antigenELISA |
| spellingShingle | Jean-Nicolas Tournier Clémence Rougeaux Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications Microorganisms anthrax toxins lethal factor edema factor protective antigen ELISA |
| title | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
| title_full | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
| title_fullStr | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
| title_full_unstemmed | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
| title_short | Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications |
| title_sort | anthrax toxin detection from in vivo studies to diagnostic applications |
| topic | anthrax toxins lethal factor edema factor protective antigen ELISA |
| url | https://www.mdpi.com/2076-2607/8/8/1103 |
| work_keys_str_mv | AT jeannicolastournier anthraxtoxindetectionfrominvivostudiestodiagnosticapplications AT clemencerougeaux anthraxtoxindetectionfrominvivostudiestodiagnosticapplications |