Central nervous system tuberculoma mimicking a brain tumor: A case report

The central nervous system (CNS) is a rare but serious site of tuberculosis spread that manifests in three forms: meningitis, spinal arachnoiditis, and CNS tuberculoma. CNS tuberculoma, or intracranial tuberculous granuloma, is a caseating or non-caseating granulomatous reaction within the brain par...

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Main Authors: Pierce McMahon, BS, David J. Pisapia, MD, Andrew D. Schweitzer, MD, Linda Heier, MD, Mark M. Souweidane, MD, Michelle Roytman, MD
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043323007860
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author Pierce McMahon, BS
David J. Pisapia, MD
Andrew D. Schweitzer, MD
Linda Heier, MD
Mark M. Souweidane, MD
Michelle Roytman, MD
author_facet Pierce McMahon, BS
David J. Pisapia, MD
Andrew D. Schweitzer, MD
Linda Heier, MD
Mark M. Souweidane, MD
Michelle Roytman, MD
author_sort Pierce McMahon, BS
collection DOAJ
description The central nervous system (CNS) is a rare but serious site of tuberculosis spread that manifests in three forms: meningitis, spinal arachnoiditis, and CNS tuberculoma. CNS tuberculoma, or intracranial tuberculous granuloma, is a caseating or non-caseating granulomatous reaction within the brain parenchyma that may mimic a brain tumor. We present the case of a 10-year-old male patient with a travel history to Western Africa who presented to our institution after his fourth tonic-clonic seizure over 2 months. MRI of the brain revealed a solitary cortical/subcortical enhancing intracranial mass with intralesional hemorrhage and mineralization, pathologically proven to represent a CNS tuberculoma. While rare, this etiology should be considered with the appropriate travel history and for which prompt treatment may improve outcomes in the pediatric population.
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spelling doaj.art-f46aaf9a71ad4b6eabd6d01fece3db622023-11-25T04:47:35ZengElsevierRadiology Case Reports1930-04332024-01-01191414417Central nervous system tuberculoma mimicking a brain tumor: A case reportPierce McMahon, BS0David J. Pisapia, MD1Andrew D. Schweitzer, MD2Linda Heier, MD3Mark M. Souweidane, MD4Michelle Roytman, MD5Department of Radiology, NewYork-Presbyterian Hospital – Weill Cornell Medicine, 525 East 68th St, New York, NY, USA; Corresponding author.Department of Pathology and Laboratory Medicine, NewYork-Presbyterian Hospital - Weill Cornell Medicine, 525 East 68th St, New York, NY, USADepartment of Radiology, NewYork-Presbyterian Hospital – Weill Cornell Medicine, 525 East 68th St, New York, NY, USADepartment of Radiology, NewYork-Presbyterian Hospital – Weill Cornell Medicine, 525 East 68th St, New York, NY, USADepartment of Neurosurgery, NewYork-Presbyterian Hospital - Weill Cornell Medicine, 525 East 68th St, New York, NY, USADepartment of Radiology, NewYork-Presbyterian Hospital – Weill Cornell Medicine, 525 East 68th St, New York, NY, USAThe central nervous system (CNS) is a rare but serious site of tuberculosis spread that manifests in three forms: meningitis, spinal arachnoiditis, and CNS tuberculoma. CNS tuberculoma, or intracranial tuberculous granuloma, is a caseating or non-caseating granulomatous reaction within the brain parenchyma that may mimic a brain tumor. We present the case of a 10-year-old male patient with a travel history to Western Africa who presented to our institution after his fourth tonic-clonic seizure over 2 months. MRI of the brain revealed a solitary cortical/subcortical enhancing intracranial mass with intralesional hemorrhage and mineralization, pathologically proven to represent a CNS tuberculoma. While rare, this etiology should be considered with the appropriate travel history and for which prompt treatment may improve outcomes in the pediatric population.http://www.sciencedirect.com/science/article/pii/S1930043323007860Central Nervous System (CNS)TuberculomaTuberculosis
spellingShingle Pierce McMahon, BS
David J. Pisapia, MD
Andrew D. Schweitzer, MD
Linda Heier, MD
Mark M. Souweidane, MD
Michelle Roytman, MD
Central nervous system tuberculoma mimicking a brain tumor: A case report
Radiology Case Reports
Central Nervous System (CNS)
Tuberculoma
Tuberculosis
title Central nervous system tuberculoma mimicking a brain tumor: A case report
title_full Central nervous system tuberculoma mimicking a brain tumor: A case report
title_fullStr Central nervous system tuberculoma mimicking a brain tumor: A case report
title_full_unstemmed Central nervous system tuberculoma mimicking a brain tumor: A case report
title_short Central nervous system tuberculoma mimicking a brain tumor: A case report
title_sort central nervous system tuberculoma mimicking a brain tumor a case report
topic Central Nervous System (CNS)
Tuberculoma
Tuberculosis
url http://www.sciencedirect.com/science/article/pii/S1930043323007860
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