Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3′-oxindoles] under Microwave Irradiation and Their Anticancer Activity

Chemo-/Regio-Selective Synthesis of Novel Functionalized Spiro[pyrrolidine-2,3′-oxindoles] under Microwave Irradiation and Their Anticancer Activity

A novel series of nitrostyrene-based spirooxindoles were synthesized via the reaction of substituted isatins <b>1a</b>–<b>b</b>, a number of α-amino acids <b>2a</b>–<b>e</b> and (E)-2-aryl-1-nitroethenes <b>3a</b>–<b>e</b> in a...

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Bibliographic Details
Main Authors:	Richa Sharma, Lalit Yadav, Ali Adnan Nasim, Ravi Kant Yadav, Rui Hong Chen, Neha Kumari, Fan Ruiqi, Ashoke Sharon, Nawal Kishore Sahu, Sirish Kumar Ippagunta, Paolo Coghi, Vincent Kam Wai Wong, Sandeep Chaudhary
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Molecules
Subjects:	anticancer spirooxindole [3+2] cycloaddition azomethine ylide microwave
Online Access:	https://www.mdpi.com/1420-3049/28/18/6503

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