Mass-Spectrometry-Based Research of Cosmetic Ingredients
Cosmetic products are chemical substances or mixtures used on the skin, hair, nails, teeth, and the mucous membranes of the oral cavity, whose use is intended to clean, protect, correct body odor, perfume, keep in good condition, or change appearance. The analysis of cosmetic ingredients is often ch...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-03-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/29/6/1336 |
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| author | Alina Florina Serb Marius Georgescu Robert Onulov Cristina Ramona Novaconi Eugen Sisu Alexandru Bolocan Raluca Elena Sandu |
| author_facet | Alina Florina Serb Marius Georgescu Robert Onulov Cristina Ramona Novaconi Eugen Sisu Alexandru Bolocan Raluca Elena Sandu |
| author_sort | Alina Florina Serb |
| collection | DOAJ |
| description | Cosmetic products are chemical substances or mixtures used on the skin, hair, nails, teeth, and the mucous membranes of the oral cavity, whose use is intended to clean, protect, correct body odor, perfume, keep in good condition, or change appearance. The analysis of cosmetic ingredients is often challenging because of their huge complexity and their adulteration. Among various analytical tools, mass spectrometry (MS) has been largely used for compound detection, ingredient screening, quality control, detection of product authenticity, and health risk evaluation. This work is focused on the MS applications in detecting and quantification of some common cosmetic ingredients, i.e., preservatives, dyes, heavy metals, allergens, and bioconjugates in various matrices (leave-on or rinse-off cosmetic products). As a global view, MS-based analysis of bioconjugates is a narrow field, and LC- and GC/GC×GC-MS are widely used for the investigation of preservatives, dyes, and fragrances, while inductively coupled plasma (ICP)-MS is ideal for comprehensive analysis of heavy metals. Ambient ionization approaches and advanced separation methods (i.e., convergence chromatography (UPC<sup>2</sup>)) coupled to MS have been proven to be an excellent choice for the analysis of scented allergens. At the same time, the current paper explores the challenges of MS-based analysis for cosmetic safety studies. |
| first_indexed | 2024-04-24T17:58:52Z |
| format | Article |
| id | doaj.art-f46b4f0ba72b4e76866938b4b18e40e6 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-04-24T17:58:52Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f46b4f0ba72b4e76866938b4b18e40e62024-03-27T13:57:05ZengMDPI AGMolecules1420-30492024-03-01296133610.3390/molecules29061336Mass-Spectrometry-Based Research of Cosmetic IngredientsAlina Florina Serb0Marius Georgescu1Robert Onulov2Cristina Ramona Novaconi3Eugen Sisu4Alexandru Bolocan5Raluca Elena Sandu6Biochemistry Discipline, Biochemistry and Pharmacology Department, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No.2, 300041 Timisoara, RomaniaPhysiology Discipline, Functional Sciences Department, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No.2, 300041 Timisoara, RomaniaFaculty of Medicine, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No.2, 300041 Timisoara, RomaniaFaculty of Medicine, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No.2, 300041 Timisoara, RomaniaBiochemistry Discipline, Biochemistry and Pharmacology Department, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No.2, 300041 Timisoara, RomaniaPhysiology Discipline, Functional Sciences Department, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No.2, 300041 Timisoara, RomaniaDepartment of Neurology, University of Medicine and Pharmacy of Craiova, St. Petru Rares, No. 2-4, 200433 Craiova, RomaniaCosmetic products are chemical substances or mixtures used on the skin, hair, nails, teeth, and the mucous membranes of the oral cavity, whose use is intended to clean, protect, correct body odor, perfume, keep in good condition, or change appearance. The analysis of cosmetic ingredients is often challenging because of their huge complexity and their adulteration. Among various analytical tools, mass spectrometry (MS) has been largely used for compound detection, ingredient screening, quality control, detection of product authenticity, and health risk evaluation. This work is focused on the MS applications in detecting and quantification of some common cosmetic ingredients, i.e., preservatives, dyes, heavy metals, allergens, and bioconjugates in various matrices (leave-on or rinse-off cosmetic products). As a global view, MS-based analysis of bioconjugates is a narrow field, and LC- and GC/GC×GC-MS are widely used for the investigation of preservatives, dyes, and fragrances, while inductively coupled plasma (ICP)-MS is ideal for comprehensive analysis of heavy metals. Ambient ionization approaches and advanced separation methods (i.e., convergence chromatography (UPC<sup>2</sup>)) coupled to MS have been proven to be an excellent choice for the analysis of scented allergens. At the same time, the current paper explores the challenges of MS-based analysis for cosmetic safety studies.https://www.mdpi.com/1420-3049/29/6/1336mass spectrometry (MS)cosmetic ingredientsLC-MSGC-MSfragrancespreservatives |
| spellingShingle | Alina Florina Serb Marius Georgescu Robert Onulov Cristina Ramona Novaconi Eugen Sisu Alexandru Bolocan Raluca Elena Sandu Mass-Spectrometry-Based Research of Cosmetic Ingredients Molecules mass spectrometry (MS) cosmetic ingredients LC-MS GC-MS fragrances preservatives |
| title | Mass-Spectrometry-Based Research of Cosmetic Ingredients |
| title_full | Mass-Spectrometry-Based Research of Cosmetic Ingredients |
| title_fullStr | Mass-Spectrometry-Based Research of Cosmetic Ingredients |
| title_full_unstemmed | Mass-Spectrometry-Based Research of Cosmetic Ingredients |
| title_short | Mass-Spectrometry-Based Research of Cosmetic Ingredients |
| title_sort | mass spectrometry based research of cosmetic ingredients |
| topic | mass spectrometry (MS) cosmetic ingredients LC-MS GC-MS fragrances preservatives |
| url | https://www.mdpi.com/1420-3049/29/6/1336 |
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