Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study
Abstract Background Kashin–Beck disease (KBD) is an endemic deformable bone and joint disease, which affects the quality of life (QOL) of patients. We conducted a cross-sectional study of the QOL of KBD patients by a new KBD quality of life (KBDQOL) questionnaire. Methods A total of 252 KBD patients...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-05-01
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| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-023-03803-8 |
| _version_ | 1797831993099026432 |
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| author | Zhankui Jin Xueyuan Wu Zhengming Sun Ming Chen Bo Yang Xianghui Dong Shizhang Liu Yanhai Chang Cuixiang Xu Zhi Yi Ming Ling |
| author_facet | Zhankui Jin Xueyuan Wu Zhengming Sun Ming Chen Bo Yang Xianghui Dong Shizhang Liu Yanhai Chang Cuixiang Xu Zhi Yi Ming Ling |
| author_sort | Zhankui Jin |
| collection | DOAJ |
| description | Abstract Background Kashin–Beck disease (KBD) is an endemic deformable bone and joint disease, which affects the quality of life (QOL) of patients. We conducted a cross-sectional study of the QOL of KBD patients by a new KBD quality of life (KBDQOL) questionnaire. Methods A total of 252 KBD patients and 248 OA patients came from Northwest China, and 260 healthy people living in the same area as KBD and osteoarthritis (OA) patients served as the controls. KBDQOL questionnaire was used to evaluate the QOL of all objects. Results The average scores for physical functions, activity limitations, support of society, mental health and general health were significantly lower in KBD patients than that in OA patients and healthy people except for economics. Monofactor analysis showed that age, height, weight status, education level and grade of KBD had a significant effect on KBDQOL score. Multivariate analysis showed that grade of KBD was the influencing factor of physical function score; gender, age, height, grade of KBD and duration of symptoms were the influencing factors of activity restriction score; age and grade of KBD were factors affecting the general health score. Conclusion The QOL of KBD patients was significantly lower than that of OA patients and healthy people. The KBDQOL questionnaire may be a promising tool for assessing the QOL of KBD patients. |
| first_indexed | 2024-04-09T14:01:43Z |
| format | Article |
| id | doaj.art-f46c53664ff84687a95533e04eee33ce |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-09T14:01:43Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-f46c53664ff84687a95533e04eee33ce2023-05-07T11:18:38ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2023-05-0118111510.1186/s13018-023-03803-8Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional studyZhankui Jin0Xueyuan Wu1Zhengming Sun2Ming Chen3Bo Yang4Xianghui Dong5Shizhang Liu6Yanhai Chang7Cuixiang Xu8Zhi Yi9Ming Ling10Department of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s Hospital Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalDepartment of Orthopaedics, Shaanxi Provincial People’s HospitalAbstract Background Kashin–Beck disease (KBD) is an endemic deformable bone and joint disease, which affects the quality of life (QOL) of patients. We conducted a cross-sectional study of the QOL of KBD patients by a new KBD quality of life (KBDQOL) questionnaire. Methods A total of 252 KBD patients and 248 OA patients came from Northwest China, and 260 healthy people living in the same area as KBD and osteoarthritis (OA) patients served as the controls. KBDQOL questionnaire was used to evaluate the QOL of all objects. Results The average scores for physical functions, activity limitations, support of society, mental health and general health were significantly lower in KBD patients than that in OA patients and healthy people except for economics. Monofactor analysis showed that age, height, weight status, education level and grade of KBD had a significant effect on KBDQOL score. Multivariate analysis showed that grade of KBD was the influencing factor of physical function score; gender, age, height, grade of KBD and duration of symptoms were the influencing factors of activity restriction score; age and grade of KBD were factors affecting the general health score. Conclusion The QOL of KBD patients was significantly lower than that of OA patients and healthy people. The KBDQOL questionnaire may be a promising tool for assessing the QOL of KBD patients.https://doi.org/10.1186/s13018-023-03803-8Kashin–Beck diseaseOsteoarthritisEndemicQuality of lifeCross-sectional studyQuestionnaire |
| spellingShingle | Zhankui Jin Xueyuan Wu Zhengming Sun Ming Chen Bo Yang Xianghui Dong Shizhang Liu Yanhai Chang Cuixiang Xu Zhi Yi Ming Ling Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study Journal of Orthopaedic Surgery and Research Kashin–Beck disease Osteoarthritis Endemic Quality of life Cross-sectional study Questionnaire |
| title | Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study |
| title_full | Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study |
| title_fullStr | Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study |
| title_full_unstemmed | Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study |
| title_short | Health-related quality of life in patients with Kashin–Beck disease is lower than in those with osteoarthritis: a cross-sectional study |
| title_sort | health related quality of life in patients with kashin beck disease is lower than in those with osteoarthritis a cross sectional study |
| topic | Kashin–Beck disease Osteoarthritis Endemic Quality of life Cross-sectional study Questionnaire |
| url | https://doi.org/10.1186/s13018-023-03803-8 |
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