Mutational robustness changes during long-term adaptation in laboratory budding yeast populations
As an adapting population traverses the fitness landscape, its local neighborhood (i.e., the collection of fitness effects of single-step mutations) can change shape because of interactions with mutations acquired during evolution. These changes to the distribution of fitness effects can affect both...
Main Authors: | Milo S Johnson, Michael M Desai |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-07-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/76491 |
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