The value of three narrow-band imaging model in the diagnosis of small colorectal polyps
Abstract This prospective study was aimed to evaluate the clinical value of narrow-band imaging (NBI), magnification endoscopy with narrow-band imaging (NBIME) and magnification endoscopy with acetic acid enhancement and narrow-band imaging (AA-NBIME) in the diagnosis of small colorectal polyps. We...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2020-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-020-78708-1 |
| _version_ | 1818754063289810944 |
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| author | Jie Sha Pin Wang Nan Sang Huiai Zhang Aiping Yang Lei Chen Zewei Gong Chao Li Yumeng Qin Xueliang Li Yong Ji Feng Gao |
| author_facet | Jie Sha Pin Wang Nan Sang Huiai Zhang Aiping Yang Lei Chen Zewei Gong Chao Li Yumeng Qin Xueliang Li Yong Ji Feng Gao |
| author_sort | Jie Sha |
| collection | DOAJ |
| description | Abstract This prospective study was aimed to evaluate the clinical value of narrow-band imaging (NBI), magnification endoscopy with narrow-band imaging (NBIME) and magnification endoscopy with acetic acid enhancement and narrow-band imaging (AA-NBIME) in the diagnosis of small colorectal polyps. We studied 261 small colorectal polyps from 122 patients with the use of above three techniques. Lesions were resected for histopathological analysis. The endoscopic images were independently reviewed by three experts and three non-experts and the diagnostic accuracy and image definition were compared among the modalities. The “experts-agreed” diagnostic accuracy was 87.7% for NBI versus 91.6% for NBIME versus 94.6% for AA-NBIME. The “non-experts-agreed” diagnostic accuracy was 80.1% for NBI versus 84.3% for NBIME versus 89.3% for AA-NBIME. All experts and non-experts diagnosed the small colorectal polyps statistically more accurately with AA-NBIME than NBI (P < 0.05). In all three modalities, the expert group’s diagnostic accuracies were statistically significantly higher compared with the non-expert group. For experts, the Kappa values for AA-NBIME, NBIME and NBI diagnosis were 0.962 (0.892–1.032), 0.577 (0.507–0.647) and 0.567 (0.497–0.637), respectively; while for nonexperts, 0.818 (0.748–0.888), 0.532 (0.462–0.602) and 0.530 (0.460–0.600). This demonstrated a good reproducibility of AA-NBIME diagnosis. The average scores (experts and non-experts) of images acquired using AA-NBIME were significantly higher than those acquired using NBIME and ME (P < 0.05). AA-NBIME is a promising tool to clearly visualize the mucosal pit pattern (PP) of colorectal polyps for better differentiating neoplastic polyps from non-neoplastic ones. |
| first_indexed | 2024-12-18T05:17:18Z |
| format | Article |
| id | doaj.art-f475f1a9a61f49c6882b61879031df17 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-18T05:17:18Z |
| publishDate | 2020-12-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj.art-f475f1a9a61f49c6882b61879031df172022-12-21T21:19:45ZengNature PortfolioScientific Reports2045-23222020-12-011011810.1038/s41598-020-78708-1The value of three narrow-band imaging model in the diagnosis of small colorectal polypsJie Sha0Pin Wang1Nan Sang2Huiai Zhang3Aiping Yang4Lei Chen5Zewei Gong6Chao Li7Yumeng Qin8Xueliang Li9Yong Ji10Feng Gao11Department of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, Nanjing Drum Tower Hospital, Affiliated Hospital of Nanjing University Medical SchoolDepartment of Gastroenterology, The Geriatric Hospital of Nanjing Medical UniversityDepartment of Gastroenterology, Taixing People’s HospitalDepartment of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical UniversityDepartment of Gastroenterology, Jingjiang People’s HospitalDepartment of Gastroenterology, Jingjiang People’s HospitalAbstract This prospective study was aimed to evaluate the clinical value of narrow-band imaging (NBI), magnification endoscopy with narrow-band imaging (NBIME) and magnification endoscopy with acetic acid enhancement and narrow-band imaging (AA-NBIME) in the diagnosis of small colorectal polyps. We studied 261 small colorectal polyps from 122 patients with the use of above three techniques. Lesions were resected for histopathological analysis. The endoscopic images were independently reviewed by three experts and three non-experts and the diagnostic accuracy and image definition were compared among the modalities. The “experts-agreed” diagnostic accuracy was 87.7% for NBI versus 91.6% for NBIME versus 94.6% for AA-NBIME. The “non-experts-agreed” diagnostic accuracy was 80.1% for NBI versus 84.3% for NBIME versus 89.3% for AA-NBIME. All experts and non-experts diagnosed the small colorectal polyps statistically more accurately with AA-NBIME than NBI (P < 0.05). In all three modalities, the expert group’s diagnostic accuracies were statistically significantly higher compared with the non-expert group. For experts, the Kappa values for AA-NBIME, NBIME and NBI diagnosis were 0.962 (0.892–1.032), 0.577 (0.507–0.647) and 0.567 (0.497–0.637), respectively; while for nonexperts, 0.818 (0.748–0.888), 0.532 (0.462–0.602) and 0.530 (0.460–0.600). This demonstrated a good reproducibility of AA-NBIME diagnosis. The average scores (experts and non-experts) of images acquired using AA-NBIME were significantly higher than those acquired using NBIME and ME (P < 0.05). AA-NBIME is a promising tool to clearly visualize the mucosal pit pattern (PP) of colorectal polyps for better differentiating neoplastic polyps from non-neoplastic ones.https://doi.org/10.1038/s41598-020-78708-1 |
| spellingShingle | Jie Sha Pin Wang Nan Sang Huiai Zhang Aiping Yang Lei Chen Zewei Gong Chao Li Yumeng Qin Xueliang Li Yong Ji Feng Gao The value of three narrow-band imaging model in the diagnosis of small colorectal polyps Scientific Reports |
| title | The value of three narrow-band imaging model in the diagnosis of small colorectal polyps |
| title_full | The value of three narrow-band imaging model in the diagnosis of small colorectal polyps |
| title_fullStr | The value of three narrow-band imaging model in the diagnosis of small colorectal polyps |
| title_full_unstemmed | The value of three narrow-band imaging model in the diagnosis of small colorectal polyps |
| title_short | The value of three narrow-band imaging model in the diagnosis of small colorectal polyps |
| title_sort | value of three narrow band imaging model in the diagnosis of small colorectal polyps |
| url | https://doi.org/10.1038/s41598-020-78708-1 |
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