Lac repressor mediated DNA looping: Monte Carlo simulation of constrained DNA molecules complemented with current experimental results.

Lac repressor mediated DNA looping: Monte Carlo simulation of constrained DNA molecules complemented with current experimental results.

Tethered particle motion (TPM) experiments can be used to detect time-resolved loop formation in a single DNA molecule by measuring changes in the length of a DNA tether. Interpretation of such experiments is greatly aided by computer simulations of DNA looping which allow one to analyze the structu...

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Bibliographic Details
Main Authors:	Yoav Y Biton, Sandip Kumar, David Dunlap, David Swigon
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4011716?pdf=render

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