Can this be considered a Fondaparinux-induced Thrombocytopenia?
We present a case of an old woman with previously documented heparin-induced thrombocytopenia (HIT), treated with fondaparinux, who presented with thrombocytopenia and venous thrombosis after exposure to a preventive dose of fondaparinux during orthopaedic surgery. Any accidental exposure to hepari...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2014-04-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | http://ejcrim.com/index.php/EJCRIM/article/view/42 |
| _version_ | 1811272848499539968 |
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| author | Barbara Mariotti Paolo Rossi Enrico Barboni |
| author_facet | Barbara Mariotti Paolo Rossi Enrico Barboni |
| author_sort | Barbara Mariotti |
| collection | DOAJ |
| description | We present a case of an old woman with previously documented heparin-induced thrombocytopenia (HIT), treated with fondaparinux, who presented with thrombocytopenia and venous thrombosis after exposure to a preventive dose of fondaparinux during orthopaedic surgery.
Any accidental exposure to heparin was avoided. Other causes of thrombocytopenia were excluded and antigenic tests combined with clinical probability made a diagnosis of HIT likely.
Can this be considered a possible case of fondaparinux-related HIT, despite the intense and early decrease in platelets, as usually happens in rapid-onset HIT, and the fact that previous exposure to fondaparinux had occurred 5 months previously? |
| first_indexed | 2024-04-12T22:47:34Z |
| format | Article |
| id | doaj.art-f47755bd46274b388d5ced6df05d301c |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-04-12T22:47:34Z |
| publishDate | 2014-04-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-f47755bd46274b388d5ced6df05d301c2022-12-22T03:13:29ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942014-04-011110.12890/2014_00004225Can this be considered a Fondaparinux-induced Thrombocytopenia?Barbara Mariotti0Paolo Rossi1Enrico Barboni2Internal Medicine Department, Azienda Ospedaliero-Universitaria S. Maria della Misericordia, UdineInternal Medicine Department, Azienda Ospedaliero-Universitaria S.Maria della Misericordia, UdineInternal Medicine Department, Azienda Ospedaliero-Universitaria S.Maria della Misericordia, UdineWe present a case of an old woman with previously documented heparin-induced thrombocytopenia (HIT), treated with fondaparinux, who presented with thrombocytopenia and venous thrombosis after exposure to a preventive dose of fondaparinux during orthopaedic surgery. Any accidental exposure to heparin was avoided. Other causes of thrombocytopenia were excluded and antigenic tests combined with clinical probability made a diagnosis of HIT likely. Can this be considered a possible case of fondaparinux-related HIT, despite the intense and early decrease in platelets, as usually happens in rapid-onset HIT, and the fact that previous exposure to fondaparinux had occurred 5 months previously?http://ejcrim.com/index.php/EJCRIM/article/view/42Thrombosis, thrombocitopenia |
| spellingShingle | Barbara Mariotti Paolo Rossi Enrico Barboni Can this be considered a Fondaparinux-induced Thrombocytopenia? European Journal of Case Reports in Internal Medicine Thrombosis, thrombocitopenia |
| title | Can this be considered a Fondaparinux-induced Thrombocytopenia? |
| title_full | Can this be considered a Fondaparinux-induced Thrombocytopenia? |
| title_fullStr | Can this be considered a Fondaparinux-induced Thrombocytopenia? |
| title_full_unstemmed | Can this be considered a Fondaparinux-induced Thrombocytopenia? |
| title_short | Can this be considered a Fondaparinux-induced Thrombocytopenia? |
| title_sort | can this be considered a fondaparinux induced thrombocytopenia |
| topic | Thrombosis, thrombocitopenia |
| url | http://ejcrim.com/index.php/EJCRIM/article/view/42 |
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