Diabetic Amyotrophy: From the Basics to the Bedside
Diabetic amyotrophy is a rare complication of diabetes compared to distal symmetric polyneuropathy, but can occasionally be encountered in clinical practice, particularly as the incidence of diabetes increases. The distinctive history of unilateral neuropathic symptoms followed rapidly by atrophy an...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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European Medical Journal
2020-03-01
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| Series: | European Medical Journal |
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| Online Access: | https://www.emjreviews.com/diabetes/article/diabetic-amyotrophy-from-the-basics-to-the-bedside/ |
| _version_ | 1818049152612827136 |
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| author | James W. Albers Ryan D. Jacobson David L. Smyth |
| author_facet | James W. Albers Ryan D. Jacobson David L. Smyth |
| author_sort | James W. Albers |
| collection | DOAJ |
| description | Diabetic amyotrophy is a rare complication of diabetes compared to distal symmetric polyneuropathy, but can occasionally be encountered in clinical practice, particularly as the incidence of diabetes increases. The distinctive history of unilateral neuropathic symptoms followed rapidly by atrophy and weakness is typical of the disorder. This complication most commonly occurs in cases of well-controlled Type 2 diabetes mellitus. While the underlying pathophysiology is known to be microvasculitic in nature, the diagnosis is often based on clinical and electrodiagnostic grounds and tissue biopsy is not typically performed. Attempts at corticosteroid administration during immunotherapy should be carefully considered on a patient-by-patient basis. Better recognition of this disorder is likely to result in more rapid diagnosis, counselling, and subspecialty referral. |
| first_indexed | 2024-12-10T10:33:02Z |
| format | Article |
| id | doaj.art-f4788d81aa0b4ba0ad3f4d53ff20dda7 |
| institution | Directory Open Access Journal |
| issn | 2397-6764 |
| language | English |
| last_indexed | 2024-12-10T10:33:02Z |
| publishDate | 2020-03-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal |
| spelling | doaj.art-f4788d81aa0b4ba0ad3f4d53ff20dda72022-12-22T01:52:31ZengEuropean Medical JournalEuropean Medical Journal2397-67642020-03-015194103Diabetic Amyotrophy: From the Basics to the BedsideJames W. Albers0Ryan D. Jacobson1David L. Smyth2University of Michigan Medical School, Ann Arbor, Michigan, USADepartment of Neurology, Rush University Medical Center, Chicago, Illinois, USADepartment of Neurology, Rush University Medical Center, Chicago, Illinois, USADiabetic amyotrophy is a rare complication of diabetes compared to distal symmetric polyneuropathy, but can occasionally be encountered in clinical practice, particularly as the incidence of diabetes increases. The distinctive history of unilateral neuropathic symptoms followed rapidly by atrophy and weakness is typical of the disorder. This complication most commonly occurs in cases of well-controlled Type 2 diabetes mellitus. While the underlying pathophysiology is known to be microvasculitic in nature, the diagnosis is often based on clinical and electrodiagnostic grounds and tissue biopsy is not typically performed. Attempts at corticosteroid administration during immunotherapy should be carefully considered on a patient-by-patient basis. Better recognition of this disorder is likely to result in more rapid diagnosis, counselling, and subspecialty referral.https://www.emjreviews.com/diabetes/article/diabetic-amyotrophy-from-the-basics-to-the-bedside/bruns–garland syndromediabetic amyotrophydiabetic lumbosacral radiculoplexus neuropathy (dlrpn) |
| spellingShingle | James W. Albers Ryan D. Jacobson David L. Smyth Diabetic Amyotrophy: From the Basics to the Bedside European Medical Journal bruns–garland syndrome diabetic amyotrophy diabetic lumbosacral radiculoplexus neuropathy (dlrpn) |
| title | Diabetic Amyotrophy: From the Basics to the Bedside |
| title_full | Diabetic Amyotrophy: From the Basics to the Bedside |
| title_fullStr | Diabetic Amyotrophy: From the Basics to the Bedside |
| title_full_unstemmed | Diabetic Amyotrophy: From the Basics to the Bedside |
| title_short | Diabetic Amyotrophy: From the Basics to the Bedside |
| title_sort | diabetic amyotrophy from the basics to the bedside |
| topic | bruns–garland syndrome diabetic amyotrophy diabetic lumbosacral radiculoplexus neuropathy (dlrpn) |
| url | https://www.emjreviews.com/diabetes/article/diabetic-amyotrophy-from-the-basics-to-the-bedside/ |
| work_keys_str_mv | AT jameswalbers diabeticamyotrophyfromthebasicstothebedside AT ryandjacobson diabeticamyotrophyfromthebasicstothebedside AT davidlsmyth diabeticamyotrophyfromthebasicstothebedside |