Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances

Objective: This paper analyze the research status and hot contents in the field related to alleviating alcoholic liver injury by medicinal and food homologous substances, and provided ideas for researchers to further in-depth study their alleviation effects on alcoholic liver injury. Methods: By usi...

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Main Authors: Qin XIANG, Guotai ZHANG, Runqing LU, Jingwen TANG, Siqiao HE, Cong MIN, Jingzhang GENG
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2024-01-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023060041
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author Qin XIANG
Guotai ZHANG
Runqing LU
Jingwen TANG
Siqiao HE
Cong MIN
Jingzhang GENG
author_facet Qin XIANG
Guotai ZHANG
Runqing LU
Jingwen TANG
Siqiao HE
Cong MIN
Jingzhang GENG
author_sort Qin XIANG
collection DOAJ
description Objective: This paper analyze the research status and hot contents in the field related to alleviating alcoholic liver injury by medicinal and food homologous substances, and provided ideas for researchers to further in-depth study their alleviation effects on alcoholic liver injury. Methods: By using the bibliometric method, the CNKI, WOS and PubMed databases as the literatures source, the distribution of literatures in the field of alleviating alcoholic liver injury from the establishment of the library to 2022 were searched and analyzed. Results: A total of 418 Chinese and English literature and 276 patents on alleviating alcoholic liver injury with drugs and food homologous substances were obtained. Domestic research in this field started late, but its development speed was fast, and the number of domestic publications and patents were higher than that of foreign countries. The trends in the number of publications and patents showed exponential and linear increase, respectively. The research hotspots mainly focused on the effect mechanism of Kudzu, Hovenia dulcis Thunb., Goji berry and other medicinal and food homologous substances in alleviating alcoholic liver injury. Conclusion: By analyzing the research status of the literature and patent, the pathogenesis of alcoholic liver injury was systematically summary, mainly relate to the ethanol metabolism, oxidative stress, immune inflammatory response and impaired intestinal barrier and dysbacteriosis. The influencing mechanism of medicinal and food homologous substances in alleviating alcoholic liver injury was mainly related to anti-lipid peroxidation, oxidative stress response, anti-inflammatory effect, scavenging of free radicals, and regulation of intestinal flora. In the future, this field would be further studied in the mechanism by network pharmacology, histological techniques and other methods.
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spelling doaj.art-f47f25a8e05f4fbaa1493685b9573a4b2024-01-11T01:27:35ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062024-01-0145211110.13386/j.issn1002-0306.20230600412023060041-2Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous SubstancesQin XIANG0Guotai ZHANG1Runqing LU2Jingwen TANG3Siqiao HE4Cong MIN5Jingzhang GENG6College of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaCollege of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaCollege of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaCollege of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaCollege of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaCollege of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaCollege of Bioscience and Bioengineering, Shaanxi University of Technology, Shaanxi Province Key Laboratory of Bio-resources, Qinling-Bashan Mountains Bioresources Comprehensive Development C.I.C, Qinba State Key Laboratory of Biological Resources and Ecological Environment, Hanzhong 723000, ChinaObjective: This paper analyze the research status and hot contents in the field related to alleviating alcoholic liver injury by medicinal and food homologous substances, and provided ideas for researchers to further in-depth study their alleviation effects on alcoholic liver injury. Methods: By using the bibliometric method, the CNKI, WOS and PubMed databases as the literatures source, the distribution of literatures in the field of alleviating alcoholic liver injury from the establishment of the library to 2022 were searched and analyzed. Results: A total of 418 Chinese and English literature and 276 patents on alleviating alcoholic liver injury with drugs and food homologous substances were obtained. Domestic research in this field started late, but its development speed was fast, and the number of domestic publications and patents were higher than that of foreign countries. The trends in the number of publications and patents showed exponential and linear increase, respectively. The research hotspots mainly focused on the effect mechanism of Kudzu, Hovenia dulcis Thunb., Goji berry and other medicinal and food homologous substances in alleviating alcoholic liver injury. Conclusion: By analyzing the research status of the literature and patent, the pathogenesis of alcoholic liver injury was systematically summary, mainly relate to the ethanol metabolism, oxidative stress, immune inflammatory response and impaired intestinal barrier and dysbacteriosis. The influencing mechanism of medicinal and food homologous substances in alleviating alcoholic liver injury was mainly related to anti-lipid peroxidation, oxidative stress response, anti-inflammatory effect, scavenging of free radicals, and regulation of intestinal flora. In the future, this field would be further studied in the mechanism by network pharmacology, histological techniques and other methods.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023060041medicinal and food homologous substancesalcoholic liver damageliteratureresearch statuspathogenesismechanism
spellingShingle Qin XIANG
Guotai ZHANG
Runqing LU
Jingwen TANG
Siqiao HE
Cong MIN
Jingzhang GENG
Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances
Shipin gongye ke-ji
medicinal and food homologous substances
alcoholic liver damage
literature
research status
pathogenesis
mechanism
title Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances
title_full Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances
title_fullStr Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances
title_full_unstemmed Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances
title_short Research Progress on the Alleviation of Alcoholic Liver Injury Based on Bibliometric Analysis of Medicinal and Food Homologous Substances
title_sort research progress on the alleviation of alcoholic liver injury based on bibliometric analysis of medicinal and food homologous substances
topic medicinal and food homologous substances
alcoholic liver damage
literature
research status
pathogenesis
mechanism
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023060041
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