Rubella antibody screening during pregnancy in an urban area of Northern Italy
Various countries have implemented anti-rubella vaccination campaigns with the main aim of preventing congenital infection. In 2003, Italy joined the European WHO programme for the elimination of congenital rubella and issued a special healthcare plan, one of the objectives of which was to reduce th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-02-01
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| Series: | Infectious Disease Reports |
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| Online Access: | http://www.pagepress.org/journals/index.php/idr/article/view/3533 |
| _version_ | 1818596222824349696 |
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| author | Massimo De Paschale Maria Teresa Manco Alessia Paganini Carlo Agrappi Paola Mirri Gabriella Cucchi Barbara Saccani Alberto Flores D’Arcais Pierangelo Clerici |
| author_facet | Massimo De Paschale Maria Teresa Manco Alessia Paganini Carlo Agrappi Paola Mirri Gabriella Cucchi Barbara Saccani Alberto Flores D’Arcais Pierangelo Clerici |
| author_sort | Massimo De Paschale |
| collection | DOAJ |
| description | Various countries have implemented anti-rubella vaccination campaigns with the main aim of preventing congenital infection. In 2003, Italy joined the European WHO programme for the elimination of congenital rubella and issued a special healthcare plan, one of the objectives of which was to reduce the proportion of rubella-susceptible pregnant women to less than 5% by 2005. The aim of this study was to determine the percentage of seronegative pregnant women after the implementation of this plan. Anti-rubella IgG and IgM antibodies were sought in 2385 pregnant women who attended our hospital for serological screening between 1 July 2008 and 30 June 2010. They included 750 women of foreign origin (31.4%). Eight percent of the women were anti-rubella seronegative: 6.2% of the Italians and 11.7% of the non-Italians. Among the women of foreign origin, the percentage of seronegativity ranged from 5.6% of those coming from Eastern Europe to 17.7% of those coming from Latin America. The level of seropositivity among women of Italian origin is high, although the objective of ensuring less than 5% of susceptible pregnant women has not yet been quite reached in our area. However, particular attention needs to be given to women coming from geographical areas characterised by different epidemiologies and vaccination strategies because the percentage of seronegativity is in some cases double that of Italian women. |
| first_indexed | 2024-12-16T11:28:29Z |
| format | Article |
| id | doaj.art-f47f68590e5748cfb9c4bac20e4666a4 |
| institution | Directory Open Access Journal |
| issn | 2036-7430 2036-7449 |
| language | English |
| last_indexed | 2024-12-16T11:28:29Z |
| publishDate | 2012-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Infectious Disease Reports |
| spelling | doaj.art-f47f68590e5748cfb9c4bac20e4666a42022-12-21T22:33:18ZengMDPI AGInfectious Disease Reports2036-74302036-74492012-02-0141e17e1710.4081/idr.2012.e172005Rubella antibody screening during pregnancy in an urban area of Northern ItalyMassimo De Paschale0Maria Teresa Manco1Alessia Paganini2Carlo Agrappi3Paola Mirri4Gabriella Cucchi5Barbara Saccani6Alberto Flores D’Arcais7Pierangelo Clerici8Microbiology Unit, Hospital of Legnano, MilanMicrobiology Unit, Hospital of Legnano, MilanMicrobiology Unit, Hospital of Legnano, MilanMicrobiology Unit, Hospital of Legnano, MilanMicrobiology Unit, Hospital of Legnano, MilanPediatric and Neonatal Unit, Hospital of Legnano, MilanPediatric and Neonatal Unit, Hospital of Legnano, MilanPediatric and Neonatal Unit, Hospital of Legnano, MilanMicrobiology Unit, Hospital of Legnano, MilanVarious countries have implemented anti-rubella vaccination campaigns with the main aim of preventing congenital infection. In 2003, Italy joined the European WHO programme for the elimination of congenital rubella and issued a special healthcare plan, one of the objectives of which was to reduce the proportion of rubella-susceptible pregnant women to less than 5% by 2005. The aim of this study was to determine the percentage of seronegative pregnant women after the implementation of this plan. Anti-rubella IgG and IgM antibodies were sought in 2385 pregnant women who attended our hospital for serological screening between 1 July 2008 and 30 June 2010. They included 750 women of foreign origin (31.4%). Eight percent of the women were anti-rubella seronegative: 6.2% of the Italians and 11.7% of the non-Italians. Among the women of foreign origin, the percentage of seronegativity ranged from 5.6% of those coming from Eastern Europe to 17.7% of those coming from Latin America. The level of seropositivity among women of Italian origin is high, although the objective of ensuring less than 5% of susceptible pregnant women has not yet been quite reached in our area. However, particular attention needs to be given to women coming from geographical areas characterised by different epidemiologies and vaccination strategies because the percentage of seronegativity is in some cases double that of Italian women.http://www.pagepress.org/journals/index.php/idr/article/view/3533Antibodiespregnancyscreeningrubellavaccination |
| spellingShingle | Massimo De Paschale Maria Teresa Manco Alessia Paganini Carlo Agrappi Paola Mirri Gabriella Cucchi Barbara Saccani Alberto Flores D’Arcais Pierangelo Clerici Rubella antibody screening during pregnancy in an urban area of Northern Italy Infectious Disease Reports Antibodies pregnancy screening rubella vaccination |
| title | Rubella antibody screening during pregnancy in an urban area of Northern Italy |
| title_full | Rubella antibody screening during pregnancy in an urban area of Northern Italy |
| title_fullStr | Rubella antibody screening during pregnancy in an urban area of Northern Italy |
| title_full_unstemmed | Rubella antibody screening during pregnancy in an urban area of Northern Italy |
| title_short | Rubella antibody screening during pregnancy in an urban area of Northern Italy |
| title_sort | rubella antibody screening during pregnancy in an urban area of northern italy |
| topic | Antibodies pregnancy screening rubella vaccination |
| url | http://www.pagepress.org/journals/index.php/idr/article/view/3533 |
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