Prediction and clinical impact of delayed lymphopenia after chemoradiotherapy in locally advanced non-small cell lung cancer

Prediction and clinical impact of delayed lymphopenia after chemoradiotherapy in locally advanced non-small cell lung cancer

IntroductionThe dosimetric factors of radiotherapy have an acute impact on the host immune system during chemoradiotherapy (CRT) in locally advanced non-small cell lung cancer (NSCLC). However, even after CRT, a substantial number of patients remain immunosuppressed with delayed lymphopenia. Therefo...

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Bibliographic Details
Main Authors: Byung-Hee Kang, Xue Li, Jaeman Son, Changhoon Song, Hyun-Cheol Kang, Hak Jae Kim, Hong-Gyun Wu, Joo Ho Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
chemoradiotherapy
lymphopenia
clinical predictor
dose-volume histograms
prediction nomogram
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.891221/full

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