Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro

Progesterone-Calcitriol Combination Enhanced Cytotoxicity of Cisplatin in Ovarian and Endometrial Cancer Cells In Vitro

Initially, patients that respond to cisplatin (DDP) treatment later relapse and develop chemoresistance. Agents that enhance DDP effectiveness will have a significant impact on cancer treatment. We have shown pronounced inhibitory effects of the progesterone-calcitriol combination on endometrial and...

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Hlavní autoři: Ana Paucarmayta, Hannah Taitz, Latoya McGlorthan, Yovanni Casablanca, G. Larry Maxwell, Kathleen M. Darcy, Viqar Syed
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2020-03-01
Edice:Biomedicines
Témata:
cisplatin
SMAD2/3
ABC transporters
gynecological cancer
multidrug resistance protein-1
On-line přístup:https://www.mdpi.com/2227-9059/8/4/73

Internet

https://www.mdpi.com/2227-9059/8/4/73

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