Inhibition of miR‐181a attenuates sepsis‐induced inflammation and apoptosis by activating Nrf2 and inhibiting NF‐κB pathways via targeting SIRT1

Abstract Sepsis is caused by microbial infection with high mortality worldwide, and characterized by multiple organ dysfunction and systemic inflammatory response. Previous study shows that miR‐181a level is increased during sepsis; however, the mechanism is still unknown. Therefore, to identify the...

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Bibliographic Details
Main Authors: Zhu Wu, Jie Chen, Wei Zhao, Chun‐Hua Zhuo, Qiong Chen
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:https://doi.org/10.1002/kjm2.12310