Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production
This paper reviews basic modern trends in obtainment of anti-rabies immunoglobulin with enhanced properties. One of these trends is associated with the substitution of organ-tissue antigen by cultural antigen at the stage of producer immunization. Analyzed are the results of research connected with...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2011-08-01
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| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/710 |
| _version_ | 1797220977747165184 |
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| author | S. V. Generalov E. G. Abramova A. K. Nikiforov Zh. V. Matveeva |
| author_facet | S. V. Generalov E. G. Abramova A. K. Nikiforov Zh. V. Matveeva |
| author_sort | S. V. Generalov |
| collection | DOAJ |
| description | This paper reviews basic modern trends in obtainment of anti-rabies immunoglobulin with enhanced properties. One of these trends is associated with the substitution of organ-tissue antigen by cultural antigen at the stage of producer immunization. Analyzed are the results of research connected with the use of the cell-cultures grown Rabies virus in production of heterologous anti-rabies immunoglobulin. The study testifies of applicability of the transferred Vero cell culture as a substrate for rabies antigen preparation. In addition to this, specified are the advantages of the rabies cultural antigen usage over the organ-tissue one at the stage of hyper-immune serum production. |
| first_indexed | 2024-03-08T13:44:57Z |
| format | Article |
| id | doaj.art-f48f22e81aba497c835fe7a13ac3b3ae |
| institution | Directory Open Access Journal |
| issn | 0370-1069 2658-719X |
| language | Russian |
| last_indexed | 2024-04-24T12:58:07Z |
| publishDate | 2011-08-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj.art-f48f22e81aba497c835fe7a13ac3b3ae2024-04-05T16:47:07ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2011-08-0104(110)767910.21055/0370-1069-2011-4(110)-76-79694Cell Structures in Heterologous Anti-Rabies Immunoglobulin ProductionS. V. Generalov0E. G. Abramova1A. K. Nikiforov2Zh. V. Matveeva3Russian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeThis paper reviews basic modern trends in obtainment of anti-rabies immunoglobulin with enhanced properties. One of these trends is associated with the substitution of organ-tissue antigen by cultural antigen at the stage of producer immunization. Analyzed are the results of research connected with the use of the cell-cultures grown Rabies virus in production of heterologous anti-rabies immunoglobulin. The study testifies of applicability of the transferred Vero cell culture as a substrate for rabies antigen preparation. In addition to this, specified are the advantages of the rabies cultural antigen usage over the organ-tissue one at the stage of hyper-immune serum production.https://journal.microbe.ru/jour/article/view/710heterologous anti-rabies immunoglobulincell culturerabies prophylaxisrabies antigen |
| spellingShingle | S. V. Generalov E. G. Abramova A. K. Nikiforov Zh. V. Matveeva Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production Проблемы особо опасных инфекций heterologous anti-rabies immunoglobulin cell culture rabies prophylaxis rabies antigen |
| title | Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production |
| title_full | Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production |
| title_fullStr | Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production |
| title_full_unstemmed | Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production |
| title_short | Cell Structures in Heterologous Anti-Rabies Immunoglobulin Production |
| title_sort | cell structures in heterologous anti rabies immunoglobulin production |
| topic | heterologous anti-rabies immunoglobulin cell culture rabies prophylaxis rabies antigen |
| url | https://journal.microbe.ru/jour/article/view/710 |
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