Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants
Exogenous RNA interference (exo-RNAi) is a powerful transgene-free tool in modern crop improvement and protection platforms. In exo-RNAi approaches, double-stranded RNAs (dsRNAs) or short-interfering RNAs (siRNAs) are externally applied in plants in order to selectively trigger degradation of target...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/9/6/673 |
| _version_ | 1797566984813019136 |
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| author | Athanasios Dalakouras Kalliope K. Papadopoulou |
| author_facet | Athanasios Dalakouras Kalliope K. Papadopoulou |
| author_sort | Athanasios Dalakouras |
| collection | DOAJ |
| description | Exogenous RNA interference (exo-RNAi) is a powerful transgene-free tool in modern crop improvement and protection platforms. In exo-RNAi approaches, double-stranded RNAs (dsRNAs) or short-interfering RNAs (siRNAs) are externally applied in plants in order to selectively trigger degradation of target mRNAs. Yet, the applied dsRNAs may also trigger unintended epigenetic alterations and result in epigenetically modified plants, an issue that has not been sufficiently addressed and which merits more careful consideration. |
| first_indexed | 2024-03-10T19:35:12Z |
| format | Article |
| id | doaj.art-f4925f222226488b96e307b448bd0785 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-10T19:35:12Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-f4925f222226488b96e307b448bd07852023-11-20T01:47:27ZengMDPI AGPlants2223-77472020-05-019667310.3390/plants9060673Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in PlantsAthanasios Dalakouras0Kalliope K. Papadopoulou1Department of Biochemistry & Biotechnology, University of Thessaly, 41500 Larissa, GreeceDepartment of Biochemistry & Biotechnology, University of Thessaly, 41500 Larissa, GreeceExogenous RNA interference (exo-RNAi) is a powerful transgene-free tool in modern crop improvement and protection platforms. In exo-RNAi approaches, double-stranded RNAs (dsRNAs) or short-interfering RNAs (siRNAs) are externally applied in plants in order to selectively trigger degradation of target mRNAs. Yet, the applied dsRNAs may also trigger unintended epigenetic alterations and result in epigenetically modified plants, an issue that has not been sufficiently addressed and which merits more careful consideration.https://www.mdpi.com/2223-7747/9/6/673exogenous RNAidsRNAssiRNAsPTGSRdDMepigenetics |
| spellingShingle | Athanasios Dalakouras Kalliope K. Papadopoulou Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants Plants exogenous RNAi dsRNAs siRNAs PTGS RdDM epigenetics |
| title | Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants |
| title_full | Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants |
| title_fullStr | Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants |
| title_full_unstemmed | Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants |
| title_short | Epigenetic Modifications: An Unexplored Facet of Exogenous RNA Application in Plants |
| title_sort | epigenetic modifications an unexplored facet of exogenous rna application in plants |
| topic | exogenous RNAi dsRNAs siRNAs PTGS RdDM epigenetics |
| url | https://www.mdpi.com/2223-7747/9/6/673 |
| work_keys_str_mv | AT athanasiosdalakouras epigeneticmodificationsanunexploredfacetofexogenousrnaapplicationinplants AT kalliopekpapadopoulou epigeneticmodificationsanunexploredfacetofexogenousrnaapplicationinplants |