Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects

Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects

Summary: SARS-CoV-2 is one of three coronaviruses that have crossed the animal-to-human barrier and caused widespread disease in the past two decades. The development of a universal human coronavirus vaccine could prevent future pandemics. We characterize 198 antibodies isolated from four COVID-19+...

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Bibliographic Details
Main Authors: Madeleine F. Jennewein, Anna J. MacCamy, Nicholas R. Akins, Junli Feng, Leah J. Homad, Nicholas K. Hurlburt, Emilie Seydoux, Yu-Hsin Wan, Andrew B. Stuart, Venkata Viswanadh Edara, Katharine Floyd, Abigail Vanderheiden, John R. Mascola, Nicole Doria-Rose, Lingshu Wang, Eun Sung Yang, Helen Y. Chu, Jonathan L. Torres, Gabriel Ozorowski, Andrew B. Ward, Rachael E. Whaley, Kristen W. Cohen, Marie Pancera, M. Juliana McElrath, Janet A. Englund, Andrés Finzi, Mehul S. Suthar, Andrew T. McGuire, Leonidas Stamatatos
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
SARS-CoV-2
SARS-CoV-1
S2 subunit
RBD
NTD
neutralization
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007294

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