Innate Immune Response in SARS-CoV-2 Infection
An efficient host immune response is crucial in controlling viral infections. Despite most studies focused on the implication of T and B cell response in COVID-19 (Corona Virus Disease-19) patients or in their activation after vaccination against SARS-CoV-2, host innate immune response has raised ev...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-02-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/10/3/501 |
| _version_ | 1797444821620621312 |
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| author | Giovanna Schiuma Silvia Beltrami Daria Bortolotti Sabrina Rizzo Roberta Rizzo |
| author_facet | Giovanna Schiuma Silvia Beltrami Daria Bortolotti Sabrina Rizzo Roberta Rizzo |
| author_sort | Giovanna Schiuma |
| collection | DOAJ |
| description | An efficient host immune response is crucial in controlling viral infections. Despite most studies focused on the implication of T and B cell response in COVID-19 (Corona Virus Disease-19) patients or in their activation after vaccination against SARS-CoV-2, host innate immune response has raised even more interest as well. In fact, innate immunity, including Natural Killer (NK) cells, monocytes/macrophages and neutrophils, represent the first line of defense against the virus and it is essential to determine the correct activation of an efficient and specific acquired immune response. In this perspective, we will report an overview on the main findings concerning SARS-CoV-2 interaction with innate host immune system, in correlation with pathogenesis and viral immune escape mechanisms. |
| first_indexed | 2024-03-09T13:17:00Z |
| format | Article |
| id | doaj.art-f493659cf6064329b22a224f595137c4 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T13:17:00Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-f493659cf6064329b22a224f595137c42023-11-30T21:35:09ZengMDPI AGMicroorganisms2076-26072022-02-0110350110.3390/microorganisms10030501Innate Immune Response in SARS-CoV-2 InfectionGiovanna Schiuma0Silvia Beltrami1Daria Bortolotti2Sabrina Rizzo3Roberta Rizzo4Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, ItalyDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, ItalyDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, ItalyDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, ItalyDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, ItalyAn efficient host immune response is crucial in controlling viral infections. Despite most studies focused on the implication of T and B cell response in COVID-19 (Corona Virus Disease-19) patients or in their activation after vaccination against SARS-CoV-2, host innate immune response has raised even more interest as well. In fact, innate immunity, including Natural Killer (NK) cells, monocytes/macrophages and neutrophils, represent the first line of defense against the virus and it is essential to determine the correct activation of an efficient and specific acquired immune response. In this perspective, we will report an overview on the main findings concerning SARS-CoV-2 interaction with innate host immune system, in correlation with pathogenesis and viral immune escape mechanisms.https://www.mdpi.com/2076-2607/10/3/501SARS-CoV-2immunityinnate immune cellsimmune-evasionnatural killer cells |
| spellingShingle | Giovanna Schiuma Silvia Beltrami Daria Bortolotti Sabrina Rizzo Roberta Rizzo Innate Immune Response in SARS-CoV-2 Infection Microorganisms SARS-CoV-2 immunity innate immune cells immune-evasion natural killer cells |
| title | Innate Immune Response in SARS-CoV-2 Infection |
| title_full | Innate Immune Response in SARS-CoV-2 Infection |
| title_fullStr | Innate Immune Response in SARS-CoV-2 Infection |
| title_full_unstemmed | Innate Immune Response in SARS-CoV-2 Infection |
| title_short | Innate Immune Response in SARS-CoV-2 Infection |
| title_sort | innate immune response in sars cov 2 infection |
| topic | SARS-CoV-2 immunity innate immune cells immune-evasion natural killer cells |
| url | https://www.mdpi.com/2076-2607/10/3/501 |
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