Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review
Aim: Head and neck squamous cell cancer (HNSCC) is the ninth most common tumor worldwide. Neck lymph node (LN) status is the major indicator of prognosis in all head and neck cancers, and the early detection of LN involvement is crucial in terms of therapy and prognosis. Diffusion-weighted imaging (...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Open Exploration Publishing Inc.
2022-12-01
|
| Series: | Exploration of Targeted Anti-tumor Therapy |
| Subjects: | |
| Online Access: | https://www.explorationpub.com/Journals/etat/Article/1002110 |
| _version_ | 1828086782342725632 |
|---|---|
| author | Maria Paola Belfiore Valerio Nardone Ida D’Onofrio Antonio Alessandro Helliot Salvia Emma D’Ippolito Luigi Gallo Valentina Caliendo Gianluca Gatta Morena Fasano Roberta Grassi Antonio Angrisani Cesare Guida Alfonso Reginelli Salvatore Cappabianca |
| author_facet | Maria Paola Belfiore Valerio Nardone Ida D’Onofrio Antonio Alessandro Helliot Salvia Emma D’Ippolito Luigi Gallo Valentina Caliendo Gianluca Gatta Morena Fasano Roberta Grassi Antonio Angrisani Cesare Guida Alfonso Reginelli Salvatore Cappabianca |
| author_sort | Maria Paola Belfiore |
| collection | DOAJ |
| description | Aim: Head and neck squamous cell cancer (HNSCC) is the ninth most common tumor worldwide. Neck lymph node (LN) status is the major indicator of prognosis in all head and neck cancers, and the early detection of LN involvement is crucial in terms of therapy and prognosis. Diffusion-weighted imaging (DWI) is a non- invasive imaging technique used in magnetic resonance imaging (MRI) to characterize tissues based on the displacement motion of water molecules. This review aims to provide an overview of the current literature concerning quantitative diffusion imaging for LN staging in patients with HNSCC.
Methods: This systematic review performed a literature search on the PubMed database (https://pubmed.ncbi.nlm.nih.gov/) for all relevant, peer-reviewed literature on the subject following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria, using the keywords: DWI, MRI, head and neck, staging, lymph node.
Results: After excluding reviews, meta-analyses, case reports, and bibliometric studies, 18 relevant papers out of the 567 retrieved were selected for analysis.
Conclusions: DWI improves the diagnosis, treatment planning, treatment response evaluation, and overall management of patients affected by HNSCC. More robust data to clarify the role of apparent diffusion coefficient (ADC) and DWI parameters are needed to develop models for prognosis and prediction in HNSCC cancer using MRI. |
| first_indexed | 2024-04-11T05:00:24Z |
| format | Article |
| id | doaj.art-f495603c7d2f441ba27e8d844710eedb |
| institution | Directory Open Access Journal |
| issn | 2692-3114 |
| language | English |
| last_indexed | 2024-04-11T05:00:24Z |
| publishDate | 2022-12-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Targeted Anti-tumor Therapy |
| spelling | doaj.art-f495603c7d2f441ba27e8d844710eedb2022-12-26T03:32:50ZengOpen Exploration Publishing Inc.Exploration of Targeted Anti-tumor Therapy2692-31142022-12-013673474510.37349/etat.2022.00110Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic reviewMaria Paola Belfiore 0https://orcid.org/0000-0001-8219-1493Valerio Nardone1https://orcid.org/0000-0002-7347-0965Ida D’Onofrio2https://orcid.org/0000-0002-4396-9466Antonio Alessandro Helliot Salvia3Emma D’Ippolito4https://orcid.org/0000-0003-2899-6447Luigi Gallo5https://orcid.org/0000-0002-5212-9207Valentina Caliendo6https://orcid.org/0000-0002-4115-2532Gianluca Gatta7https://orcid.org/0000-0003-0874-8294Morena Fasano8https://orcid.org/0000-0003-0782-8778Roberta Grassi9https://orcid.org/0000-0002-4322-8115Antonio Angrisani10https://orcid.org/0000-0003-4470-7561Cesare Guida11https://orcid.org/0000-0003-3687-2006Alfonso Reginelli12https://orcid.org/0000-0003-4809-6235Salvatore Cappabianca13https://orcid.org/0000-0002-5417-2268Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyUnit of Radiation Oncology, Ospedale del Mare, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyUnit of Radiation Oncology, Ospedale del Mare, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyAim: Head and neck squamous cell cancer (HNSCC) is the ninth most common tumor worldwide. Neck lymph node (LN) status is the major indicator of prognosis in all head and neck cancers, and the early detection of LN involvement is crucial in terms of therapy and prognosis. Diffusion-weighted imaging (DWI) is a non- invasive imaging technique used in magnetic resonance imaging (MRI) to characterize tissues based on the displacement motion of water molecules. This review aims to provide an overview of the current literature concerning quantitative diffusion imaging for LN staging in patients with HNSCC. Methods: This systematic review performed a literature search on the PubMed database (https://pubmed.ncbi.nlm.nih.gov/) for all relevant, peer-reviewed literature on the subject following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) criteria, using the keywords: DWI, MRI, head and neck, staging, lymph node. Results: After excluding reviews, meta-analyses, case reports, and bibliometric studies, 18 relevant papers out of the 567 retrieved were selected for analysis. Conclusions: DWI improves the diagnosis, treatment planning, treatment response evaluation, and overall management of patients affected by HNSCC. More robust data to clarify the role of apparent diffusion coefficient (ADC) and DWI parameters are needed to develop models for prognosis and prediction in HNSCC cancer using MRI.https://www.explorationpub.com/Journals/etat/Article/1002110diffusion-weighted imagingmagnetic resonance imaginghead and neck cancerhead and neck squamous cell cancerlymph node |
| spellingShingle | Maria Paola Belfiore Valerio Nardone Ida D’Onofrio Antonio Alessandro Helliot Salvia Emma D’Ippolito Luigi Gallo Valentina Caliendo Gianluca Gatta Morena Fasano Roberta Grassi Antonio Angrisani Cesare Guida Alfonso Reginelli Salvatore Cappabianca Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review Exploration of Targeted Anti-tumor Therapy diffusion-weighted imaging magnetic resonance imaging head and neck cancer head and neck squamous cell cancer lymph node |
| title | Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review |
| title_full | Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review |
| title_fullStr | Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review |
| title_full_unstemmed | Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review |
| title_short | Diffusion-weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis: a systematic review |
| title_sort | diffusion weighted imaging and apparent diffusion coefficient mapping of head and neck lymph node metastasis a systematic review |
| topic | diffusion-weighted imaging magnetic resonance imaging head and neck cancer head and neck squamous cell cancer lymph node |
| url | https://www.explorationpub.com/Journals/etat/Article/1002110 |
| work_keys_str_mv | AT mariapaolabelfiore diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT valerionardone diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT idadonofrio diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT antonioalessandrohelliotsalvia diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT emmadippolito diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT luigigallo diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT valentinacaliendo diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT gianlucagatta diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT morenafasano diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT robertagrassi diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT antonioangrisani diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT cesareguida diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT alfonsoreginelli diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview AT salvatorecappabianca diffusionweightedimagingandapparentdiffusioncoefficientmappingofheadandnecklymphnodemetastasisasystematicreview |