cPLA<sub>2</sub>α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation

cPLA<sub>2</sub>α Enzyme Inhibition Attenuates Inflammation and Keratinocyte Proliferation

As a regulator of cellular inflammation and proliferation, cytosolic phospholipase A<sub>2</sub> α (cPLA<sub>2</sub>α) is a promising therapeutic target for psoriasis; indeed, the cPLA<sub>2</sub>α inhibitor AVX001 has shown efficacy against plaque psoriasis in a...

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Bibliographic Details
Main Authors: Felicity J. Ashcroft, Nur Mahammad, Helene Midtun Flatekvål, Astrid J. Feuerherm, Berit Johansen
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
cPLA<sub>2</sub>α
psoriasis
proliferation
anti-inflammatory
Online Access:https://www.mdpi.com/2218-273X/10/10/1402

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