Recombinant Acetylcholine Receptor Immunization Induces a Robust Model of Experimental Autoimmune Myasthenia Gravis in Mice

Recombinant Acetylcholine Receptor Immunization Induces a Robust Model of Experimental Autoimmune Myasthenia Gravis in Mice

Myasthenia gravis (MG) is a prototypical autoimmune disease of the neuromuscular junction (NMJ). The study of the underlying pathophysiology has provided novel insights into the interplay of autoantibodies and complement-mediated tissue damage. Experimental autoimmune myasthenia gravis (EAMG) emerge...

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Bibliographic Details
Main Authors: Lukas Theissen, Christina B. Schroeter, Niklas Huntemann, Saskia Räuber, Vera Dobelmann, Derya Cengiz, Alexander Herrmann, Kathrin Koch-Hölsken, Norbert Gerdes, Hao Hu, Philipp Mourikis, Amin Polzin, Malte Kelm, Hans-Peter Hartung, Sven G. Meuth, Christopher Nelke, Tobias Ruck
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
myasthenia gravis
complement
murine model
experimental autoimmune myasthenia gravis
Online Access:https://www.mdpi.com/2073-4409/13/6/508

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