Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review

Major depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss of interest, imposing a significant economic burden on health systems and society. Impaired sleep is both a symptom and a risk factor for depression. Natural astaxanthin (AST)...

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Main Authors: Yi-Fan Peng, Lin-Lin Wang, Juan-Hua Gu, Yue-Qin Zeng
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023054968
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author Yi-Fan Peng
Lin-Lin Wang
Juan-Hua Gu
Yue-Qin Zeng
author_facet Yi-Fan Peng
Lin-Lin Wang
Juan-Hua Gu
Yue-Qin Zeng
author_sort Yi-Fan Peng
collection DOAJ
description Major depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss of interest, imposing a significant economic burden on health systems and society. Impaired sleep is both a symptom and a risk factor for depression. Natural astaxanthin (AST), a carotenoid primarily derived from algae and aquatic animals, possesses multiple pharmacological properties such as anti-inflammatory, anti-apoptotic, and antioxidant stress effects. Prior research suggests that AST may have antidepressant properties. This mini-review highlights the potential mechanisms by which AST can prevent depression, providing novel insights into drug research for depression treatment. Specifically, this mechanism suggests that astaxanthin may improve sleep and thus potentially aid in the treatment of depression.
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spelling doaj.art-f49920251e784fcea49670363b9d70702023-07-27T05:59:10ZengElsevierHeliyon2405-84402023-07-0197e18288Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-reviewYi-Fan Peng0Lin-Lin Wang1Juan-Hua Gu2Yue-Qin Zeng3Academy of Biomedical Engineering, Kunming Medical University, Kunming, 650500, ChinaAcademy of Biomedical Engineering, Kunming Medical University, Kunming, 650500, ChinaAcademy of Biomedical Engineering, Kunming Medical University, Kunming, 650500, ChinaCorresponding author. Academy of Biomedical Engineering, Kunming Medical University, Kunming, China.; Academy of Biomedical Engineering, Kunming Medical University, Kunming, 650500, ChinaMajor depressive disorder (MDD) is a prevalent psychiatric condition that results in persistent feelings of sadness and loss of interest, imposing a significant economic burden on health systems and society. Impaired sleep is both a symptom and a risk factor for depression. Natural astaxanthin (AST), a carotenoid primarily derived from algae and aquatic animals, possesses multiple pharmacological properties such as anti-inflammatory, anti-apoptotic, and antioxidant stress effects. Prior research suggests that AST may have antidepressant properties. This mini-review highlights the potential mechanisms by which AST can prevent depression, providing novel insights into drug research for depression treatment. Specifically, this mechanism suggests that astaxanthin may improve sleep and thus potentially aid in the treatment of depression.http://www.sciencedirect.com/science/article/pii/S2405844023054968AstaxanthinDepressionCircadian rhythmSleep
spellingShingle Yi-Fan Peng
Lin-Lin Wang
Juan-Hua Gu
Yue-Qin Zeng
Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
Heliyon
Astaxanthin
Depression
Circadian rhythm
Sleep
title Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_full Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_fullStr Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_full_unstemmed Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_short Effects of astaxanthin on depressive and sleep symptoms: A narrative mini-review
title_sort effects of astaxanthin on depressive and sleep symptoms a narrative mini review
topic Astaxanthin
Depression
Circadian rhythm
Sleep
url http://www.sciencedirect.com/science/article/pii/S2405844023054968
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