Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications

Cyclodextrins have gained significant and established attention as versatile carriers for the delivery of bioactive compounds derived from natural sources in various applications, including medicine, food and cosmetics. Their toroidal structure and hydrophobic cavity render them ideal candidates for...

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Main Authors: Stamatia Christaki, Eleni Spanidi, Eleni Panagiotidou, Sophia Athanasopoulou, Anastasia Kyriakoudi, Ioannis Mourtzinos, Konstantinos Gardikis
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/9/1274
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author Stamatia Christaki
Eleni Spanidi
Eleni Panagiotidou
Sophia Athanasopoulou
Anastasia Kyriakoudi
Ioannis Mourtzinos
Konstantinos Gardikis
author_facet Stamatia Christaki
Eleni Spanidi
Eleni Panagiotidou
Sophia Athanasopoulou
Anastasia Kyriakoudi
Ioannis Mourtzinos
Konstantinos Gardikis
author_sort Stamatia Christaki
collection DOAJ
description Cyclodextrins have gained significant and established attention as versatile carriers for the delivery of bioactive compounds derived from natural sources in various applications, including medicine, food and cosmetics. Their toroidal structure and hydrophobic cavity render them ideal candidates for encapsulating and solubilizing hydrophobic and poorly soluble compounds. Most medicinal, food and cosmetic ingredients share the challenges of hydrophobicity and degradation that can be effectively addressed by various cyclodextrin types. Though not new or novel—their first applications appeared in the market in the 1970s—their versatility has inspired numerous developments, either on the academic or industrial level. This review article provides an overview of the ever-growing applications of cyclodextrins in the delivery of bioactive compounds from natural sources and their potential application benefits.
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spelling doaj.art-f49a8ba803aa4beabfb01258f733d6df2023-11-19T12:25:02ZengMDPI AGPharmaceuticals1424-82472023-09-01169127410.3390/ph16091274Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics ApplicationsStamatia Christaki0Eleni Spanidi1Eleni Panagiotidou2Sophia Athanasopoulou3Anastasia Kyriakoudi4Ioannis Mourtzinos5Konstantinos Gardikis6Laboratory of Food Chemistry and Biochemistry, School of Agriculture, Aristotle University of Thessaloniki (AUTH), 54124 Thessaloniki, GreeceAPIVITA SA, Industrial Park, Markopoulo, 19003 Athens, GreeceAPIVITA SA, Industrial Park, Markopoulo, 19003 Athens, GreeceAPIVITA SA, Industrial Park, Markopoulo, 19003 Athens, GreeceLaboratory of Food Chemistry and Biochemistry, School of Agriculture, Aristotle University of Thessaloniki (AUTH), 54124 Thessaloniki, GreeceLaboratory of Food Chemistry and Biochemistry, School of Agriculture, Aristotle University of Thessaloniki (AUTH), 54124 Thessaloniki, GreeceAPIVITA SA, Industrial Park, Markopoulo, 19003 Athens, GreeceCyclodextrins have gained significant and established attention as versatile carriers for the delivery of bioactive compounds derived from natural sources in various applications, including medicine, food and cosmetics. Their toroidal structure and hydrophobic cavity render them ideal candidates for encapsulating and solubilizing hydrophobic and poorly soluble compounds. Most medicinal, food and cosmetic ingredients share the challenges of hydrophobicity and degradation that can be effectively addressed by various cyclodextrin types. Though not new or novel—their first applications appeared in the market in the 1970s—their versatility has inspired numerous developments, either on the academic or industrial level. This review article provides an overview of the ever-growing applications of cyclodextrins in the delivery of bioactive compounds from natural sources and their potential application benefits.https://www.mdpi.com/1424-8247/16/9/1274encapsulationcarriersstabilitypolyphenolspackagingsupplements
spellingShingle Stamatia Christaki
Eleni Spanidi
Eleni Panagiotidou
Sophia Athanasopoulou
Anastasia Kyriakoudi
Ioannis Mourtzinos
Konstantinos Gardikis
Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications
Pharmaceuticals
encapsulation
carriers
stability
polyphenols
packaging
supplements
title Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications
title_full Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications
title_fullStr Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications
title_full_unstemmed Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications
title_short Cyclodextrins for the Delivery of Bioactive Compounds from Natural Sources: Medicinal, Food and Cosmetics Applications
title_sort cyclodextrins for the delivery of bioactive compounds from natural sources medicinal food and cosmetics applications
topic encapsulation
carriers
stability
polyphenols
packaging
supplements
url https://www.mdpi.com/1424-8247/16/9/1274
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