TLR5-deficiency controls dendritic cell subset development in an autoimmune diabetes-susceptible model

IntroductionThe incidence of the autoimmune disease, type 1 diabetes (T1D), has been increasing worldwide and recent studies have shown that the gut microbiota are associated with modulating susceptibility to T1D. Toll-like receptor 5 (TLR5) recognizes bacterial flagellin and is widely expressed on...

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Bibliographic Details
Main Authors: James Alexander Pearson, Youjia Hu, Jian Peng, F. Susan Wong, Li Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1333967/full