A model-based clustering via mixture of hierarchical models with covariate adjustment for detecting differentially expressed genes from paired design

Abstract The causes of many complex human diseases are still largely unknown. Genetics plays an important role in uncovering the molecular mechanisms of complex human diseases. A key step to characterize the genetics of a complex human disease is to unbiasedly identify disease-associated gene transc...

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Bibliographic Details
Main Authors: Yixin Zhang, Wei Liu, Weiliang Qiu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05556-x