Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study

Background/Aims We investigated the impact of obesity on the clinical outcomes following percutaneous coronary intervention (PCI). Methods We included South Koreans aged > 20 years who underwent the Korean National Health Screening assessment between 2009 and 2012. Obesity was defined using the b...

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Main Authors: Woo-Hyuk Song, Eun Hui Bae, Jeong Cheon Ahn, Tae Ryom Oh, Yong-Hyun Kim, Jin Seok Kim, Sun-Won Kim, Soo Wan Kim, Kyung-Do Han, Sang Yup Lim
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2021-03-01
Series:The Korean Journal of Internal Medicine
Subjects:
Online Access:http://www.kjim.org/upload/pdf/kjim-2020-099.pdf
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author Woo-Hyuk Song
Eun Hui Bae
Jeong Cheon Ahn
Tae Ryom Oh
Yong-Hyun Kim
Jin Seok Kim
Sun-Won Kim
Soo Wan Kim
Kyung-Do Han
Sang Yup Lim
author_facet Woo-Hyuk Song
Eun Hui Bae
Jeong Cheon Ahn
Tae Ryom Oh
Yong-Hyun Kim
Jin Seok Kim
Sun-Won Kim
Soo Wan Kim
Kyung-Do Han
Sang Yup Lim
author_sort Woo-Hyuk Song
collection DOAJ
description Background/Aims We investigated the impact of obesity on the clinical outcomes following percutaneous coronary intervention (PCI). Methods We included South Koreans aged > 20 years who underwent the Korean National Health Screening assessment between 2009 and 2012. Obesity was defined using the body mass index (BMI), according to the World Health Organization’s recommendations. Abdominal obesity was defined using the waist circumference (WC), as defined by the Korean Society for Obesity. The odds and hazard ratios in all-cause mortality were calculated after adjustment for multiple covariates. Patients were followed up to the end of 2017. Results Among 130,490 subjects who underwent PCI, the mean age negatively correlated with BMI. WC, hypertension, diabetes, dyslipidemia, fasting glucose, total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels correlated with the increased BMI. The mortality rates were higher in the lower BMI and WC groups than the higher BMI and WC groups. The non-obese with abdominal obesity group showed a mortality rate of 2.11 per 1,000 person-years. Obese with no abdominal obesity group had the lowest mortality rate (0.88 per 1,000 person-years). The mortality showed U-shaped curve with a cut-off value of 29 in case of BMI and 78 cm of WC. Conclusions The mortality showed U-shaped curve and the cut-off value of lowest mortality was 29 in case of BMI and 78 cm of WC. The abdominal obesity may be associated with poor prognosis in Korean patients who underwent PCI.
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spelling doaj.art-f49ff8256a854df78c89453a0723f6a02022-12-21T22:58:03ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482021-03-0136Suppl 1S90S9810.3904/kjim.2020.099170474Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based studyWoo-Hyuk Song0Eun Hui Bae1Jeong Cheon Ahn2Tae Ryom Oh3Yong-Hyun Kim4Jin Seok Kim5Sun-Won Kim6Soo Wan Kim7Kyung-Do Han8Sang Yup Lim9 Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea Department of Internal Medicine, Korea University Ansan Hospital, Ansan, KoreaBackground/Aims We investigated the impact of obesity on the clinical outcomes following percutaneous coronary intervention (PCI). Methods We included South Koreans aged > 20 years who underwent the Korean National Health Screening assessment between 2009 and 2012. Obesity was defined using the body mass index (BMI), according to the World Health Organization’s recommendations. Abdominal obesity was defined using the waist circumference (WC), as defined by the Korean Society for Obesity. The odds and hazard ratios in all-cause mortality were calculated after adjustment for multiple covariates. Patients were followed up to the end of 2017. Results Among 130,490 subjects who underwent PCI, the mean age negatively correlated with BMI. WC, hypertension, diabetes, dyslipidemia, fasting glucose, total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels correlated with the increased BMI. The mortality rates were higher in the lower BMI and WC groups than the higher BMI and WC groups. The non-obese with abdominal obesity group showed a mortality rate of 2.11 per 1,000 person-years. Obese with no abdominal obesity group had the lowest mortality rate (0.88 per 1,000 person-years). The mortality showed U-shaped curve with a cut-off value of 29 in case of BMI and 78 cm of WC. Conclusions The mortality showed U-shaped curve and the cut-off value of lowest mortality was 29 in case of BMI and 78 cm of WC. The abdominal obesity may be associated with poor prognosis in Korean patients who underwent PCI.http://www.kjim.org/upload/pdf/kjim-2020-099.pdfobesitycoronary artery diseasemortality
spellingShingle Woo-Hyuk Song
Eun Hui Bae
Jeong Cheon Ahn
Tae Ryom Oh
Yong-Hyun Kim
Jin Seok Kim
Sun-Won Kim
Soo Wan Kim
Kyung-Do Han
Sang Yup Lim
Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
The Korean Journal of Internal Medicine
obesity
coronary artery disease
mortality
title Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
title_full Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
title_fullStr Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
title_full_unstemmed Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
title_short Effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention: a nationwide, population-based study
title_sort effect of body mass index and abdominal obesity on mortality after percutaneous coronary intervention a nationwide population based study
topic obesity
coronary artery disease
mortality
url http://www.kjim.org/upload/pdf/kjim-2020-099.pdf
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