Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study
BackgroundCardiac dysfunction is a well-established risk factor for contrast-associated acute kidney injury (CA-AKI). Nevertheless, the relationship between cardiac remodeling, as assessed by echocardiography, and CA-AKI remains uncertain.MethodA total of 3,241 patients undergoing coronary angiograp...
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Frontiers Media S.A.
2023-11-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1173586/full |
| _version_ | 1827775136179159040 |
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| author | Qingqing Chen Duanbin Li Duanbin Li Hangpan Jiang Tianli Hu Yecheng Tao Changqing Du Wenbin Zhang Wenbin Zhang |
| author_facet | Qingqing Chen Duanbin Li Duanbin Li Hangpan Jiang Tianli Hu Yecheng Tao Changqing Du Wenbin Zhang Wenbin Zhang |
| author_sort | Qingqing Chen |
| collection | DOAJ |
| description | BackgroundCardiac dysfunction is a well-established risk factor for contrast-associated acute kidney injury (CA-AKI). Nevertheless, the relationship between cardiac remodeling, as assessed by echocardiography, and CA-AKI remains uncertain.MethodA total of 3,241 patients undergoing coronary angiography (CAG) with/without percutaneous coronary intervention (PCI) were enrolled in this retrospective study. Collected echocardiographic parameters were normalized by body surface area (BSA) and divided according to quartile, including the left ventricular internal end-diastolic diameter index (LVIDDI), left ventricular internal end-systolic diameter index (LVIDSI), and left ventricular mass index (LVMI). Logistic regression analysis was conducted to ascertain the association between structural parameter changes and CA-AKI. Further investigation was performed in different subgroups.ResultsThe mean age of the participants was 66.6 years, and 16.3% suffered from CA-AKI. LVIDSI [≥22.9 mm/m2: OR = 1.953, 95%CI (1.459 to 2.615), P < 0.001], LVIDDI [≥33.2 mm/m2: OR = 1.443, 95%CI (1.087 to 1.914), P = 0.011], and LVMI [≥141.0 g/m2: OR = 1.530, 95%CI (1.146 to 2.044), P = 0.004] in quartile were positively associated with CA-AKI risk in general (all P for trend <0.05). These associations were consistent when stratified by age, left ventricular ejection fraction, estimated glomerular filtration rate, and N-terminal brain natriuretic peptide (all P for interaction >0.05). The presence of eccentric hypertrophy [OR = 1.400, 95%CI (1.093 to 1.793), P = 0.008] and the coexistence of hypertrophy and dilation [OR = 1.397, 95%CI (1.091 to 1.789), P = 0.008] carried a higher CA-AKI risk.ConclusionThe presence of cardiac remodeling, assessed by echocardiography, is associated with a higher risk of CA-AKI. |
| first_indexed | 2024-03-11T13:47:47Z |
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| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-03-11T13:47:47Z |
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| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-f4a1c782db8d4d5eb3a930303d89357f2023-11-02T10:11:23ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-11-011010.3389/fcvm.2023.11735861173586Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section studyQingqing Chen0Duanbin Li1Duanbin Li2Hangpan Jiang3Tianli Hu4Yecheng Tao5Changqing Du6Wenbin Zhang7Wenbin Zhang8Department of Cardiology, Affiliated Zhejiang Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, ChinaDepartment of Cardiology, The Fourth Affiliated Hospital, College of Medicine, Zhejiang University, Yiwu, ChinaDepartment of Cardiology, The Fourth Affiliated Hospital, College of Medicine, Zhejiang University, Yiwu, ChinaDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Cardiology, Affiliated Zhejiang Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, ChinaKey Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, ChinaBackgroundCardiac dysfunction is a well-established risk factor for contrast-associated acute kidney injury (CA-AKI). Nevertheless, the relationship between cardiac remodeling, as assessed by echocardiography, and CA-AKI remains uncertain.MethodA total of 3,241 patients undergoing coronary angiography (CAG) with/without percutaneous coronary intervention (PCI) were enrolled in this retrospective study. Collected echocardiographic parameters were normalized by body surface area (BSA) and divided according to quartile, including the left ventricular internal end-diastolic diameter index (LVIDDI), left ventricular internal end-systolic diameter index (LVIDSI), and left ventricular mass index (LVMI). Logistic regression analysis was conducted to ascertain the association between structural parameter changes and CA-AKI. Further investigation was performed in different subgroups.ResultsThe mean age of the participants was 66.6 years, and 16.3% suffered from CA-AKI. LVIDSI [≥22.9 mm/m2: OR = 1.953, 95%CI (1.459 to 2.615), P < 0.001], LVIDDI [≥33.2 mm/m2: OR = 1.443, 95%CI (1.087 to 1.914), P = 0.011], and LVMI [≥141.0 g/m2: OR = 1.530, 95%CI (1.146 to 2.044), P = 0.004] in quartile were positively associated with CA-AKI risk in general (all P for trend <0.05). These associations were consistent when stratified by age, left ventricular ejection fraction, estimated glomerular filtration rate, and N-terminal brain natriuretic peptide (all P for interaction >0.05). The presence of eccentric hypertrophy [OR = 1.400, 95%CI (1.093 to 1.793), P = 0.008] and the coexistence of hypertrophy and dilation [OR = 1.397, 95%CI (1.091 to 1.789), P = 0.008] carried a higher CA-AKI risk.ConclusionThe presence of cardiac remodeling, assessed by echocardiography, is associated with a higher risk of CA-AKI.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1173586/fullechocardiographycardiac remodelingcontrast associated acute kidney injurycoronary angiographypercutaneous coronary intervention |
| spellingShingle | Qingqing Chen Duanbin Li Duanbin Li Hangpan Jiang Tianli Hu Yecheng Tao Changqing Du Wenbin Zhang Wenbin Zhang Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study Frontiers in Cardiovascular Medicine echocardiography cardiac remodeling contrast associated acute kidney injury coronary angiography percutaneous coronary intervention |
| title | Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study |
| title_full | Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study |
| title_fullStr | Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study |
| title_full_unstemmed | Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study |
| title_short | Cardiac remodeling on echocardiogram is related to contrast-associated acute kidney injury after coronary angiography: a cross-section study |
| title_sort | cardiac remodeling on echocardiogram is related to contrast associated acute kidney injury after coronary angiography a cross section study |
| topic | echocardiography cardiac remodeling contrast associated acute kidney injury coronary angiography percutaneous coronary intervention |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1173586/full |
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