Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review
Background. Measures of exercise capacity, frailty, and physical function are commonly used in lung transplant candidates and recipients to evaluate their physical limitations and the effects of exercise training and to select candidates for transplantation. It is unclear how these measures are rela...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2022-11-01
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| Series: | Transplantation Direct |
| Online Access: | http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001385 |
| _version_ | 1797986962748997632 |
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| author | Nicholas Bourgeois, MSc Shirin M. Shallwani, MSc Fahad S. Al-Huda, MA (Cantab) Sunita Mathur, PhD Charles Poirier, MD Tania Janaudis-Ferreira, PhD |
| author_facet | Nicholas Bourgeois, MSc Shirin M. Shallwani, MSc Fahad S. Al-Huda, MA (Cantab) Sunita Mathur, PhD Charles Poirier, MD Tania Janaudis-Ferreira, PhD |
| author_sort | Nicholas Bourgeois, MSc |
| collection | DOAJ |
| description | Background. Measures of exercise capacity, frailty, and physical function are commonly used in lung transplant candidates and recipients to evaluate their physical limitations and the effects of exercise training and to select candidates for transplantation. It is unclear how these measures are related to clinical outcomes and healthcare utilization before and after lung transplantation. The purpose of this scoping review was to describe how measures of exercise capacity, physical function, and frailty are related to pre- and posttransplant outcomes.
Methods. We considered studies of any design that included performance-based tests of exercise capacity, physical function, and frailty in adult lung transplant candidates or recipients. Outcomes of interest were clinical outcomes (eg, mortality, quality of life) and healthcare utilization.
Results. Seventy-two articles met the inclusion criteria. The 6-min walk test (6MWT) was shown to be related to mortality on the waiting list with different distance values as cutoffs points. There were inconsistent results regarding the relationship of the 6MWT with other clinical outcomes. Few studies have examined the relationship between the cardiopulmonary exercise test or the short physical performance battery and clinical outcomes, although some studies have shown relationship with survival posttransplant and quality of life. Few studies examined the relationship between the tests of interest and healthcare utilization‚ and the results were inconsistent.
Conclusions. Except for the relationship between the 6MWT and mortality on the waiting list, there is limited evidence regarding the relationship of performance-based measures of exercise capacity, frailty, and physical function with clinical outcomes or healthcare utilization. |
| first_indexed | 2024-04-11T07:41:18Z |
| format | Article |
| id | doaj.art-f4a2ec66e33445d9859bd5ba0ee1a275 |
| institution | Directory Open Access Journal |
| issn | 2373-8731 |
| language | English |
| last_indexed | 2024-04-11T07:41:18Z |
| publishDate | 2022-11-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Transplantation Direct |
| spelling | doaj.art-f4a2ec66e33445d9859bd5ba0ee1a2752022-12-22T04:36:35ZengWolters KluwerTransplantation Direct2373-87312022-11-01811e138510.1097/TXD.0000000000001385202211000-00005Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping ReviewNicholas Bourgeois, MSc0Shirin M. Shallwani, MSc1Fahad S. Al-Huda, MA (Cantab)2Sunita Mathur, PhD3Charles Poirier, MD4Tania Janaudis-Ferreira, PhD51 Lung Transplant Program, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada.3 School of Rehabilitation Sciences, University of Ottawa, Ottawa, ON, Canada.4 Faculty of Biology Medicine and Health, School of Medicine, The University of Manchester, Manchester, United Kingdom.5 School of Rehabilitation Therapy, Queen’s University, Kingston, ON, Canada.1 Lung Transplant Program, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada.2 School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada.Background. Measures of exercise capacity, frailty, and physical function are commonly used in lung transplant candidates and recipients to evaluate their physical limitations and the effects of exercise training and to select candidates for transplantation. It is unclear how these measures are related to clinical outcomes and healthcare utilization before and after lung transplantation. The purpose of this scoping review was to describe how measures of exercise capacity, physical function, and frailty are related to pre- and posttransplant outcomes. Methods. We considered studies of any design that included performance-based tests of exercise capacity, physical function, and frailty in adult lung transplant candidates or recipients. Outcomes of interest were clinical outcomes (eg, mortality, quality of life) and healthcare utilization. Results. Seventy-two articles met the inclusion criteria. The 6-min walk test (6MWT) was shown to be related to mortality on the waiting list with different distance values as cutoffs points. There were inconsistent results regarding the relationship of the 6MWT with other clinical outcomes. Few studies have examined the relationship between the cardiopulmonary exercise test or the short physical performance battery and clinical outcomes, although some studies have shown relationship with survival posttransplant and quality of life. Few studies examined the relationship between the tests of interest and healthcare utilization‚ and the results were inconsistent. Conclusions. Except for the relationship between the 6MWT and mortality on the waiting list, there is limited evidence regarding the relationship of performance-based measures of exercise capacity, frailty, and physical function with clinical outcomes or healthcare utilization.http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001385 |
| spellingShingle | Nicholas Bourgeois, MSc Shirin M. Shallwani, MSc Fahad S. Al-Huda, MA (Cantab) Sunita Mathur, PhD Charles Poirier, MD Tania Janaudis-Ferreira, PhD Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review Transplantation Direct |
| title | Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review |
| title_full | Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review |
| title_fullStr | Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review |
| title_full_unstemmed | Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review |
| title_short | Relationship of Exercise Capacity, Physical Function, and Frailty Measures With Clinical Outcomes and Healthcare Utilization in Lung Transplantation: A Scoping Review |
| title_sort | relationship of exercise capacity physical function and frailty measures with clinical outcomes and healthcare utilization in lung transplantation a scoping review |
| url | http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001385 |
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