Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program
Background: World Health Organization (WHO) declared tuberculosis (TB) as a global public health emergency and recommended DOTS as a standard strategy for controlling the disease. TB is one of the major causes of infectious diseases in the world, and 25% of all avoidable deaths in developing countri...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | International Journal of Mycobacteriology |
| Subjects: | |
| Online Access: | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=117;epage=118;aulast=Sisay |
| _version_ | 1828158206452432896 |
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| author | Solomon Sisay Belete Mengistu Woldargay Erku Desalegne Woldeyohannes |
| author_facet | Solomon Sisay Belete Mengistu Woldargay Erku Desalegne Woldeyohannes |
| author_sort | Solomon Sisay |
| collection | DOAJ |
| description | Background: World Health Organization (WHO) declared tuberculosis (TB) as a global public health emergency and recommended DOTS as a standard strategy for controlling the disease. TB is one of the major causes of infectious diseases in the world, and 25% of all avoidable deaths in developing countries. About a third of the world's population is estimated to be infected with tubercle bacilli, and hence at risk of developing active disease. The objective of the study was, therefore, to evaluate the impact of DOTS strategy on smear-positive pulmonary tuberculosis case finding and their treatment outcomes in Gambella Regional State, Ethiopia.
Methods: A retrospective health facility-based descriptive study was employed. Quarterly data were collected by using WHO structured reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in the region.
Results: A total of 10,024 TB cases (all forms) were registered and reported between the periods from 2003 up to 2012. Out of these, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760 (27.5%) had extra-pulmonary TB. An average case detection rate (CDR)1 CDR: Percentage of smear-positive TB cases detected among the total number of TB cases estimated to occur. 1 of 40.9% (SD=0.1) and treatment success rate (TSR)2 TSR: A sum of TB cases who completed treatment and who declared cured 2 of 55.7% (SD=0.28) for smear-positive pulmonary TB including other forms of TB were reported for the specified years period. Additionally, the average mean values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively.
Conclusions: The recommended TSR set by WHO was achieved as it was already been fulfilled more than 85% from 2009 up to 2011 in the region and the reported CDR was far below (40.9%) for smear-positive pulmonary TB including other forms of TB from the target. Therefore, extensive efforts should be established to maintain the achieved TSR and to increase the low level of CDR for all forms of TB cases through implementing alternative case finding strategies. |
| first_indexed | 2024-04-11T23:40:39Z |
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| institution | Directory Open Access Journal |
| issn | 2212-5531 2212-554X |
| language | English |
| last_indexed | 2024-04-11T23:40:39Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Mycobacteriology |
| spelling | doaj.art-f4a5c6e926c44766947685263b80e2d92022-12-22T03:56:48ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2016-01-015511711810.1016/j.ijmyco.2016.11.003Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control programSolomon SisayBelete MengistuWoldargay ErkuDesalegne WoldeyohannesBackground: World Health Organization (WHO) declared tuberculosis (TB) as a global public health emergency and recommended DOTS as a standard strategy for controlling the disease. TB is one of the major causes of infectious diseases in the world, and 25% of all avoidable deaths in developing countries. About a third of the world's population is estimated to be infected with tubercle bacilli, and hence at risk of developing active disease. The objective of the study was, therefore, to evaluate the impact of DOTS strategy on smear-positive pulmonary tuberculosis case finding and their treatment outcomes in Gambella Regional State, Ethiopia. Methods: A retrospective health facility-based descriptive study was employed. Quarterly data were collected by using WHO structured reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in the region. Results: A total of 10,024 TB cases (all forms) were registered and reported between the periods from 2003 up to 2012. Out of these, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760 (27.5%) had extra-pulmonary TB. An average case detection rate (CDR)1 CDR: Percentage of smear-positive TB cases detected among the total number of TB cases estimated to occur. 1 of 40.9% (SD=0.1) and treatment success rate (TSR)2 TSR: A sum of TB cases who completed treatment and who declared cured 2 of 55.7% (SD=0.28) for smear-positive pulmonary TB including other forms of TB were reported for the specified years period. Additionally, the average mean values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively. Conclusions: The recommended TSR set by WHO was achieved as it was already been fulfilled more than 85% from 2009 up to 2011 in the region and the reported CDR was far below (40.9%) for smear-positive pulmonary TB including other forms of TB from the target. Therefore, extensive efforts should be established to maintain the achieved TSR and to increase the low level of CDR for all forms of TB cases through implementing alternative case finding strategies.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=117;epage=118;aulast=SisayGambella regionCase detection rateDirectly Observed Treatment Short-courseTreatment success rateTuberculosis |
| spellingShingle | Solomon Sisay Belete Mengistu Woldargay Erku Desalegne Woldeyohannes Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program International Journal of Mycobacteriology Gambella region Case detection rate Directly Observed Treatment Short-course Treatment success rate Tuberculosis |
| title | Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program |
| title_full | Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program |
| title_fullStr | Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program |
| title_full_unstemmed | Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program |
| title_short | Ten years' experience of directly observed treatment short-course (DOTS) in Gambella Regional State, Ethiopia: An evaluation of tuberculosis control program |
| title_sort | ten years experience of directly observed treatment short course dots in gambella regional state ethiopia an evaluation of tuberculosis control program |
| topic | Gambella region Case detection rate Directly Observed Treatment Short-course Treatment success rate Tuberculosis |
| url | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2016;volume=5;issue=5;spage=117;epage=118;aulast=Sisay |
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