An observational study of extending FOLFOX chemotherapy, lengthening the interval between radiotherapy and surgery, and enhancing pathological complete response rates in rectal cancer patients following preoperative chemoradiotherapy

An observational study of extending FOLFOX chemotherapy, lengthening the interval between radiotherapy and surgery, and enhancing pathological complete response rates in rectal cancer patients following preoperative chemoradiotherapy

Introduction: Patients with rectal cancer who exhibit a pathologic complete response to preoperative concurrent chemoradiotherapy have excellent oncologic outcomes. In this study, we evaluated the potential advantages of adding oxaliplatin to preoperative fluoropyrimidine-based chemoradiotherapy adm...

Full description

Bibliographic Details
Main Authors:	Chun-Ming Huang, Ming-Yii Huang, Hsiang-Lin Tsai, Ching-Wen Huang, Cheng-Jen Ma, Yung-Sung Yeh, Suh-Hang Juo, Chih-Jen Huang, Jaw-Yuan Wang
Format:	Article
Language:	English
Published:	SAGE Publishing 2016-09-01
Series:	Therapeutic Advances in Gastroenterology
Online Access:	https://doi.org/10.1177/1756283X16656690

Similar Items

Comparison of efficacy and safety of preoperative Chemoradiotherapy in locally advanced upper and middle/lower rectal cancer
by: Ming-Yii Huang, et al.
Published: (2018-03-01)

Surgical treatment following neoadjuvant chemoradiotherapy in locally advanced rectal cancer
by: Ming‐Yii Huang, et al.
Published: (2020-03-01)

Optimal time intervals between preoperative radiotherapy or chemoradiotherapy and surgery in rectal cancer?
by: Bengt eGlimelius
Published: (2014-04-01)

Time interval between the completion of radiotherapy and robotic-assisted surgery among patients with stage I-III rectal cancer undergoing preoperative chemoradiotherapy.
by: Ching-Wen Huang, et al.
Published: (2020-01-01)

HIF-1α Expression Increases Preoperative Concurrent Chemoradiotherapy Resistance in Hyperglycemic Rectal Cancer
by: Yi-Jung Huang, et al.
Published: (2022-08-01)

Biomarkers of Favorable vs. Unfavorable Responses in Locally Advanced Rectal Cancer Patients Receiving Neoadjuvant Concurrent Chemoradiotherapy
by: Hsin-Hua Lee, et al.
Published: (2022-05-01)

Pretreatment Neutrophil-to-Lymphocyte Ratio Associated with Tumor Recurrence and Survival in Patients Achieving a Pathological Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer
by: Chun-Ming Huang, et al.
Published: (2021-09-01)

Efficacy of concurrent radiotherapy in patients with locally advanced rectal cancer and synchronous metastasis receiving systemic therapy
by: Tzu-Chieh Yin, et al.
Published: (2023-03-01)

Neoadjuvant Chemoradiotherapy for Locally Advanced Gastric Cancer: Where Are We at?
by: Jen-Hao Yeh, et al.
Published: (2022-06-01)

Oral fluorpyrimidines in preoperative chemoradiotherapy for operable rectal cancer
by: Yu. A. Barsukov, et al.
Published: (2016-01-01)

A review of preoperative chemoradiotherapy for lower rectal cancer
by: Naohito Beppu, et al.
Published: (2017-07-01)

Artemis as Predictive Biomarker of Responsiveness to Preoperative Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer
by: Hai Liu, et al.
Published: (2024-01-01)

The Impact of Radiotherapy Dose in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma Receiving Preoperative Chemoradiotherapy
by: Chien-Ming Lo, et al.
Published: (2021-03-01)

Radiotherapy in the preoperative neoadjuvant treatment of locally advanced rectal cancer
by: Zhen Yu, et al.
Published: (2023-11-01)

Effect of interval between preoperative radiotherapy and surgery on clinical outcome and radiation proctitis in rectal cancer from FOWARC trial
by: Yi‐Kan Cheng, et al.
Published: (2020-02-01)

Preoperative sequential short-course radiation therapy and FOLFOX chemotherapy versus long-course chemoradiotherapy for locally advanced rectal cancer: a multicenter, randomized controlled trial (SOLAR trial)
by: Min Kyu Kang, et al.
Published: (2023-11-01)

Rectal adenocarcinoma with oncocytic features: possible relationship with preoperative chemoradiotherapy.
by: Rouzbahman, M, et al.
Published: (2006)

Organ preservation for early rectal cancer using preoperative chemoradiotherapy
by: Gyung Mo Son
Published: (2023-06-01)

Electron stream effect in 0.35 Tesla magnetic resonance image guided radiotherapy for breast cancer
by: Hsin-Hua Lee, et al.
Published: (2023-07-01)

The functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapse.
by: I-Ping Yang, et al.
Published: (2013-01-01)

Oncological outcomes of robotic-assisted total mesorectal excision after neoadjuvant concurrent chemoradiotherapy in patients with rectal cancer
by: Po-Jung Chen, et al.
Published: (2021-07-01)

p53 status and the regression of rectal cancer following preoperative chemoradiotherapy
by: Wheeler, J, et al.
Published: (2000)

Beware of Early Relapse in Rectal Cancer Patients Treated With Preoperative Chemoradiotherapy
by: Seul Gi Oh, et al.
Published: (2020-12-01)

Overexpression of MLPH in Rectal Cancer Patients Correlates with a Poorer Response to Preoperative Chemoradiotherapy and Reduced Patient Survival
by: Wan-Shan Li, et al.
Published: (2021-11-01)

Cost-effectiveness analysis of long-course oxaliplatin and bolus of fluorouracil based preoperative chemoradiotherapy vs. 5x5Gy radiation plus FOLFOX4 for locally advanced resectable rectal cancer
by: Shichao Wang, et al.
Published: (2019-06-01)

Lincp21-RNA as Predictive Response Marker for Preoperative Chemoradiotherapy in Rectal Cancer
by: Jose Carlos Benitez, et al.
Published: (2021-05-01)

Usefulness of close surveillance for rectal cancer patients after neoadjuvant chemoradiotherapy
by: Hsu Yu-Jen, et al.
Published: (2022-09-01)

Comparing neoadjuvant long-course chemoradiotherapy with short-course radiotherapy in rectal cancer
by: Jian Wang, et al.
Published: (2021-07-01)

Efficacy of preoperative chemoradiotherapy in patients with cT2N0 distal rectal cancer
by: Min Young Park, et al.
Published: (2023-06-01)

Translational Potential of MicroRNAs for Preoperative Staging and Prediction of Chemoradiotherapy Response in Rectal Cancer
by: Tana Machackova, et al.
Published: (2019-10-01)

Correlation between T stage and lymph node metastasis in rectal cancer treated with preoperative chemoradiotherapy
by: Seijong Kim, et al.
Published: (2022-10-01)

Role of IDO expression in patients with locally advanced rectal cancer treated with preoperative chemoradiotherapy
by: Chie Takasu, et al.
Published: (2022-12-01)

Alpha-fetoprotein-producing rectal cancer successfully responded to preoperative chemoradiotherapy: case report
by: Yuki Nakamura, et al.
Published: (2018-09-01)

Oncologic Outcomes of Organ Preserving Approaches in Patients With Rectal Cancer Treated With Preoperative Chemoradiotherapy
by: In Ja Park, et al.
Published: (2019-04-01)

Comparative Outcomes of Preoperative Chemoradiotherapy and Selective Postoperative Chemoradiotherapy in Clinical Stage T3N0 Low and Mid Rectal Cancer
by: Yu Lin, et al.
Published: (2019-10-01)

PINCH is an independent prognostic factor in rectal cancer patients without preoperative radiotherapy - a study in a Swedish rectal cancer trial of preoperative radiotherapy
by: Holmqvist Annica, et al.
Published: (2012-02-01)

Preoperative chemoradiotherapy with capecitabine and triweekly oxaliplatin versus capecitabine monotherapy for locally advanced rectal cancer: a propensity-score matched study
by: Anchuan Li, et al.
Published: (2022-07-01)

Composition of fecal microbiota in low-set rectal cancer patients treated with FOLFOX
by: Jing Li, et al.
Published: (2020-02-01)

Prognostic and Predictive Biomarkers in Patients with Locally Advanced Rectal Cancer (LARC) Treated with Preoperative Chemoradiotherapy
by: Alfonso Martín-Carnicero, et al.
Published: (2022-10-01)

Utility of RGNEF in the Prediction of Clinical Prognosis in Patients with Rectal Cancer Receiving Preoperative Concurrent Chemoradiotherapy
by: Chih-I. Chen, et al.
Published: (2021-12-01)