Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity

This case illustrates the exceedingly rare phenomenon of transient diabetes insipidus, in association with pre-eclampsia, occurring in the post-partum period following an in vitro fertilisation pregnancy, in an otherwise well 48-year-old lady. Diabetes insipidus can manifest during pregnancy, induce...

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Main Authors: Natassia Rodrigo, Samantha Hocking
Format: Article
Language:English
Published: Bioscientifica 2018-05-01
Series:Endocrinology, Diabetes & Metabolism Case Reports
Online Access:https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-18-0052
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author Natassia Rodrigo
Samantha Hocking
author_facet Natassia Rodrigo
Samantha Hocking
author_sort Natassia Rodrigo
collection DOAJ
description This case illustrates the exceedingly rare phenomenon of transient diabetes insipidus, in association with pre-eclampsia, occurring in the post-partum period following an in vitro fertilisation pregnancy, in an otherwise well 48-year-old lady. Diabetes insipidus can manifest during pregnancy, induced by increased vasopressinase activity secreted by placental trophoblasts and usually manifests in the third trimester. This presentation elucidates not only the intricate balance between the physiology of pregnancy and hormonal homeostasis, but also the importance of post-partum care as the physiological changes of pregnancy still hold pathological potential in the weeks immediately following delivery.
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spelling doaj.art-f4a654d419e343f293617e12d5d6e3612022-12-21T18:20:44ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732052-05732018-05-01111410.1530/EDM-18-0052Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activityNatassia Rodrigo0Samantha Hocking1Department of Endocrinology and Diabetes, Royal North Shore Hospital, Sydney, and University of Sydney, Sydney, AustraliaDepartment of Endocrinology and Diabetes, Royal North Shore Hospital, Sydney, and University of Sydney, Sydney, AustraliaThis case illustrates the exceedingly rare phenomenon of transient diabetes insipidus, in association with pre-eclampsia, occurring in the post-partum period following an in vitro fertilisation pregnancy, in an otherwise well 48-year-old lady. Diabetes insipidus can manifest during pregnancy, induced by increased vasopressinase activity secreted by placental trophoblasts and usually manifests in the third trimester. This presentation elucidates not only the intricate balance between the physiology of pregnancy and hormonal homeostasis, but also the importance of post-partum care as the physiological changes of pregnancy still hold pathological potential in the weeks immediately following delivery.https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-18-0052
spellingShingle Natassia Rodrigo
Samantha Hocking
Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity
Endocrinology, Diabetes & Metabolism Case Reports
title Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity
title_full Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity
title_fullStr Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity
title_full_unstemmed Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity
title_short Transient diabetes insipidus in a post-partum woman with pre-eclampsia associated with residual placental vasopressinase activity
title_sort transient diabetes insipidus in a post partum woman with pre eclampsia associated with residual placental vasopressinase activity
url https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-18-0052
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