C-terminal telopeptide procollagen type I change in patients with atrial fibrillation
Method: C-terminal telopeptide procollagen type –I (CTTP-I) was used as a marker for collagen synthesis. The study group comprised 69 people and the control group 23. Results: Patients with persistent and chronic AF had an elevated level of CTTP-I in comparison with patients with paroxysmal AF (0.4...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2017-03-01
|
| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6230 |
| _version_ | 1818623180021956608 |
|---|---|
| author | A. V. Goryachiy A. I. Gozhenko E. M. Levchenko V. V. Goriachyi M. A. Kuznetsova M. I. Arapu |
| author_facet | A. V. Goryachiy A. I. Gozhenko E. M. Levchenko V. V. Goriachyi M. A. Kuznetsova M. I. Arapu |
| author_sort | A. V. Goryachiy |
| collection | DOAJ |
| description | Method: C-terminal telopeptide procollagen type –I (CTTP-I) was used as a marker for collagen synthesis. The study group comprised 69 people and the control group 23.
Results: Patients with persistent and chronic AF had an elevated level of CTTP-I in comparison with patients with paroxysmal AF (0.40+0.19 ng/ml, 0.44+0.21 ng/ml vs 0.36+0.17 ng/ml, p=0.016). The level of CTTP-I was significantly lower in the control group compared to patients with paroxysmal, persistent and chronic AF forms (0.36+0.17 ng/ml, 0.40+0.19 ng/ml, 0.44+0.21 ng/ml and 0.27+0.11ng/ml , p=0.016).
Conclusions: The level of CTTP-I is significantly different between healthy people and patients with AF. Moreover, these markers also differ depending on the AF form. It can be assumed that the intensity of extracellular synthesis and degradation of type I collagen can be related to the severity and type of AF. |
| first_indexed | 2024-12-16T18:36:57Z |
| format | Article |
| id | doaj.art-f4b19dd2027a4c91a95d1e94e31bd439 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-16T18:36:57Z |
| publishDate | 2017-03-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-f4b19dd2027a4c91a95d1e94e31bd4392022-12-21T22:21:09ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-03-017388289110.5281/zenodo.14728185621C-terminal telopeptide procollagen type I change in patients with atrial fibrillationA. V. Goryachiy0A. I. Gozhenko1E. M. Levchenko2V. V. Goriachyi3M. A. Kuznetsova4M. I. Arapu5Odessa Regional Clinical HospitalUkrainian Research Institute of Transport MedicineOdessa Regional Clinical HospitalOdessa Regional Clinical HospitalOdessa Regional Clinical HospitalOdessa Regional Clinical HospitalMethod: C-terminal telopeptide procollagen type –I (CTTP-I) was used as a marker for collagen synthesis. The study group comprised 69 people and the control group 23. Results: Patients with persistent and chronic AF had an elevated level of CTTP-I in comparison with patients with paroxysmal AF (0.40+0.19 ng/ml, 0.44+0.21 ng/ml vs 0.36+0.17 ng/ml, p=0.016). The level of CTTP-I was significantly lower in the control group compared to patients with paroxysmal, persistent and chronic AF forms (0.36+0.17 ng/ml, 0.40+0.19 ng/ml, 0.44+0.21 ng/ml and 0.27+0.11ng/ml , p=0.016). Conclusions: The level of CTTP-I is significantly different between healthy people and patients with AF. Moreover, these markers also differ depending on the AF form. It can be assumed that the intensity of extracellular synthesis and degradation of type I collagen can be related to the severity and type of AF.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6230atrial fibrillation, cardiovascular diseases, c-terminal telopeptide collagen type i |
| spellingShingle | A. V. Goryachiy A. I. Gozhenko E. M. Levchenko V. V. Goriachyi M. A. Kuznetsova M. I. Arapu C-terminal telopeptide procollagen type I change in patients with atrial fibrillation Journal of Education, Health and Sport atrial fibrillation, cardiovascular diseases, c-terminal telopeptide collagen type i |
| title | C-terminal telopeptide procollagen type I change in patients with atrial fibrillation |
| title_full | C-terminal telopeptide procollagen type I change in patients with atrial fibrillation |
| title_fullStr | C-terminal telopeptide procollagen type I change in patients with atrial fibrillation |
| title_full_unstemmed | C-terminal telopeptide procollagen type I change in patients with atrial fibrillation |
| title_short | C-terminal telopeptide procollagen type I change in patients with atrial fibrillation |
| title_sort | c terminal telopeptide procollagen type i change in patients with atrial fibrillation |
| topic | atrial fibrillation, cardiovascular diseases, c-terminal telopeptide collagen type i |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/6230 |
| work_keys_str_mv | AT avgoryachiy cterminaltelopeptideprocollagentypeichangeinpatientswithatrialfibrillation AT aigozhenko cterminaltelopeptideprocollagentypeichangeinpatientswithatrialfibrillation AT emlevchenko cterminaltelopeptideprocollagentypeichangeinpatientswithatrialfibrillation AT vvgoriachyi cterminaltelopeptideprocollagentypeichangeinpatientswithatrialfibrillation AT makuznetsova cterminaltelopeptideprocollagentypeichangeinpatientswithatrialfibrillation AT miarapu cterminaltelopeptideprocollagentypeichangeinpatientswithatrialfibrillation |