A genomic-based approach combining in vivo selection in mice to identify a novel virulence gene in Leishmania.
Infection with Leishmania results in a broad spectrum of pathologies where L. infantum and L. donovani cause fatal visceral leishmaniasis and L. major causes destructive cutaneous lesions. The identification and characterization of Leishmania virulence genes may define the genetic basis for these di...
| Main Authors: | , , |
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| פורמט: | Article |
| שפה: | English |
| יצא לאור: |
Public Library of Science (PLoS)
2008-06-01
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| סדרה: | PLoS Neglected Tropical Diseases |
| גישה מקוונת: | http://europepmc.org/articles/PMC2398785?pdf=render |