Development and evaluation of calcium alginate beads prepared by sequential and simultaneous methods

Development and evaluation of calcium alginate beads prepared by sequential and simultaneous methods

The objective of this study was to develop a sustained release dosage form of Trimetazidine dihydrochloride (TMZ) using a natural polymeric carrier prepared in a completely aqueous environment. TMZ was entrapped in calcium alginate beads prepared with sodium alginate by the ionotropic gelation metho...

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Bibliographic Details
Main Authors:	Sanchita Mandal, S. Senthil Kumar, Balakrishnam Krishnamoorthy, Sanat Kumar Basu
Format:	Article
Language:	English
Published:	Universidade de São Paulo 2010-12-01
Series:	Brazilian Journal of Pharmaceutical Sciences
Subjects:	Alginato de sódio Beads de alginato de cálcio Dicloridrato de trimetazidina Gelatinização ionotrópica Sodium alginate Calcium alginate beads Trimetazidine dihydrochloride Ionotropic gelation
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400021

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